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SALGININ BA\u015eLANGICI VE SEYR\u0130
Yemek yerken bir anda hareketsiz kald\u0131\u011f\u0131n\u0131z\u0131 ve uykuya dald\u0131\u011f\u0131n\u0131z\u0131 d\u00fc\u015f\u00fcn\u00fcn hem de y\u0131llarca s\u00fcrecek
bir uyku . 1900\u00b4l\u00fc y\u0131llarda ya\u015fayan milyonlarca insan tam olarak bunu ya\u015fad\u0131. 1916 Verdun
Muharebesi\u00b4nde g\u00f6rev yapan bir askerin birdenbire hareket kabiliyetini kaybetmesi ile ba\u015flayan
salg\u0131n k\u0131sa bir s\u00fcrede t\u00fcm d\u00fcnyaya yay\u0131ld\u0131. Hastalar\u0131n yapt\u0131\u011f\u0131 tek \u015fey uyumakt\u0131. Bitmek t\u00fckenmek
bilmeksizin uyumak\u2026 \u00dcstelik doktorlar\u0131n hastalara tan\u0131 koymak i\u00e7in girdi\u011fi t\u00fcm m\u00fccadeleler de
sonu\u00e7suz kal\u0131yordu. Hastalar\u0131n y\u00fczlerinde spazm olu\u015fuyordu ve uyansalar dahi sanki y\u00fczlerinde \u00f6l\u00fc
gibi kaskat\u0131 bir ifade oluyordu. Ard\u0131ndan neden oldu\u011fu bilinmese de zamanla salg\u0131n\u0131n seyri azalmaya
ba\u015flad\u0131 .Hastalar\u0131n neredeyse 1\/3\u2019\u00fc iyile\u015fti ama nas\u0131l ve neden iyile\u015ftikleri bilinmiyordu . Aradan uzun
y\u0131llar ge\u00e7tikten sonra 1993 y\u0131l\u0131nda bir ki\u015fi aniden hastaland\u0131. Y\u00fcksek ate\u015fi vard\u0131 ve hal\u00fcsinasyonlar
g\u00f6r\u00fcyordu. Doktorlar\u0131n yapt\u0131\u011f\u0131 g\u00f6zlemlere g\u00f6re uyku hastal\u0131\u011f\u0131 kendini yeniden g\u00f6stermi\u015fti ve nedeni
ayn\u0131 o zamanki gibi gizemli ve bilinmezdi. Sonralar\u0131 bu hasta t\u0131pk\u0131 bu hastal\u0131\u011f\u0131 \u00f6nceden ya\u015fayan
insanlarda oldu\u011fu gibi yava\u015f yava\u015f iyile\u015fmeye ba\u015flad\u0131 ve 6 sene sonra tamamen eski haline d\u00f6nd\u00fc.
G\u00fcn\u00fcm\u00fczde hala bu hastal\u0131\u011f\u0131 ara\u015ft\u0131r\u0131p gizemini \u00e7\u00f6zmek isteyen bilim insanlar\u0131 var ama \u015fu an d\u00fcnya
\u00fczerinde bu hastal\u0131\u011fa yakalanm\u0131\u015f kimse olmad\u0131\u011f\u0131 i\u00e7in ara\u015ft\u0131rmalar s\u00fcrd\u00fcr\u00fclemiyor<\/p>\n\n\n
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<\/figure><\/div>\n\n\nSALGININ \u0130ZLER\u0130 SALGININ EDEB\u0130YAT VE S\u0130NEMADA YANSIMALARI : UYANI\u015eLAR KAYNAK\u00c7A 1900 l\u00fc y\u0131llarda ya\u015fayan y\u00fczbinlerce insan\u0131n \u00f6l\u00fcm\u00fcne sebep olan ve g\u00fcn\u00fcm\u00fczde hala gizemini koruyan ensefalit lethargica salg\u0131n\u0131 nas\u0131l ortaya \u00e7\u0131km\u0131\u015ft\u0131r ? Salg\u0131ndan y\u0131llar sonra kurbanlar\u0131n g\u00f6z\u00fcnden edebiyata ve sinemaya yans\u0131malar\u0131 nas\u0131l olmu\u015ftur inceleyelim<\/p>\n","protected":false},"author":1827,"featured_media":14646,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[1],"tags":[725,2457],"acf":[],"views":155,"_links":{"self":[{"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/posts\/14626"}],"collection":[{"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/users\/1827"}],"replies":[{"embeddable":true,"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/comments?post=14626"}],"version-history":[{"count":1,"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/posts\/14626\/revisions"}],"predecessor-version":[{"id":14642,"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/posts\/14626\/revisions\/14642"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/media\/14646"}],"wp:attachment":[{"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/media?parent=14626"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/categories?post=14626"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/tags?post=14626"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
Uyku hastal\u0131\u011f\u0131 , iyile\u015femeyen hastalarda; ate\u015f, bo\u011faz a\u011fr\u0131s\u0131 gibi semptomlarla ilerleyen akut fazdan
Parkinson benzeri belirtiler ile karakterize kronik faza do\u011fru evriliyordu . Ve \u00e7o\u011fu hasta hayatlar\u0131n\u0131n
geri kalan\u0131n\u0131 Parkinson hastal\u0131\u011f\u0131na da benzeyen katatonik bir halde s\u00fcrd\u00fcyord\u00fc. Ta ki Oliver Sacks\u00b4\u0131n
mucize ilac\u0131 L-DOPA ya kadar. 1960\u2019larda N\u00f6rolog ve yazar Oliver Sacks Ensefalit lethargica \u00fczerine
\u00e7al\u0131\u015fmalar yapmaya ba\u015flad\u0131 ve baz\u0131 hastalar\u0131 ila\u00e7la tedavi etmeyi ba\u015fard\u0131 fakat sonunda yine bu
hastalar hastal\u0131\u011fa yenik d\u00fc\u015ft\u00fc ve katatonik durumlar\u0131na geri d\u00f6nd\u00fcler . Yine de hastalar\u0131n mucizevi
ila\u00e7 L-DOPA ile ya\u015fad\u0131\u011f\u0131 uyan\u0131\u015flar Ensefalit lethargica i\u00e7in bir d\u00f6n\u00fcm noktas\u0131 olmu\u015ftu. Bu d\u00f6n\u00fcm
noktas\u0131, o ana kadar hastal\u0131k \u00fczerinde kaydedilmi\u015f en b\u00fcy\u00fck geli\u015fmeydi. Dolay\u0131s\u0131yla Oliver Sacks\u00b4\u0131n
hastalar \u00fczerindeki deneysel tedavisi kendi kaleminden edebiyata daha sonralar\u0131 da sinemaya konu
oldu. Sacks, bu hastalar \u00fczerindeki g\u00f6zlemlerini ve deneyimlerini UYANI\u015eLAR ad\u0131n\u0131 verdi\u011fi kitab\u0131nda
ele ald\u0131. Bu hikaye 1990 y\u0131l\u0131nda da UYANI\u015eLAR kitab\u0131ndan ayn\u0131 isim ile beyaz perdeye uyarland\u0131<\/p>\n\n\n\n![\"\"](\"https:\/\/blog.ulubat.org\/wp-content\/uploads\/2023\/12\/WhatsApp-Image-2023-12-05-at-23.34.38-1024x1024.jpeg\")
Uyan\u0131\u015flar: 1920’lerde d\u00fcnyan\u0131n \u00e7e\u015fitli yerlerinde g\u00f6r\u00fclen “uyku hastal\u0131\u011f\u0131” salg\u0131n\u0131n\u0131n kurban\u0131
olan yirmi hastan\u0131n, k\u0131rk y\u0131l sonra Doktor Sacks’\u0131n g\u00f6zetiminde ald\u0131klar\u0131 “mucize ila\u00e7” LDOPA sayesinde inan\u0131lmaz bir \u015fekilde “uyanmalar\u0131n\u0131n” hikayesini ele al\u0131r. Oliver Sacks
filmdeki ismi ile Dr. Malcolm Sayer, \u00e7al\u0131\u015ft\u0131\u011f\u0131 klinikte uzun y\u0131llard\u0131r katatonik halde olan 20
hasta ile tan\u0131\u015f\u0131r. \u015eu ana kadar hastalar \u00fczerinde bir\u00e7ok tedavi denenmi\u015ftir fakat hi\u00e7birine
yan\u0131t al\u0131namam\u0131\u015ft\u0131r. Hasta yak\u0131nlar\u0131 da dahil doktorlar ve klinik \u00e7al\u0131\u015fanlar\u0131n\u0131n hepsi bu
durumu kabullenmi\u015ftir ve hastalar i\u00e7in \u00f6z bak\u0131mlar\u0131n\u0131 kar\u015f\u0131lamaktan ba\u015fka yapacak bir \u015fey
kalmam\u0131\u015ft\u0131r. Hastalar\u0131n bak\u0131m\u0131n\u0131n s\u00fcrd\u00fcr\u00fcld\u00fc\u011f\u00fc klini\u011fe gelip hastalar \u00fczerinde bolca g\u00f6zlem
yapma f\u0131rsat\u0131 yakalayan Oliver Sacks, g\u00f6zlemleri ve dikkati sonucu hastalar\u0131n t\u00fcm\u00fcn\u00fcn
ge\u00e7mi\u015finde ensefalit oldu\u011funu g\u00f6r\u00fcr. Katatonik durumda olan hastalar Parkinson benzeri
semptomlar g\u00f6sterdi\u011fi i\u00e7in Dr. Sacks, Parkinson hastalar\u0131 i\u00e7in de kullan\u0131lan mucizevi ila\u00e7 LDOPA\u2019y\u0131 1969 y\u0131l\u0131nda hastalar\u0131na deneysel olarak vermeye karar verir. Hastalar ald\u0131klar\u0131 LDOPA n\u0131n etkisi ile uyan\u0131\u015flar ya\u015fay\u0131p normal hayata d\u00f6nmeye ba\u015flarlar fakat sonralar\u0131
tekrardan hastal\u0131\u011fa yenik d\u00fc\u015ferler. Dr. Sacks ve ekibi post ensefalit hastalar\u0131yla \u00e7al\u0131\u015fmaya
devam eder. Piyasaya \u00e7\u0131kan yeni ila\u00e7 tedavilerini denemeye devam ederler. Hastalar\u0131n
bir\u00e7o\u011fu k\u0131sa s\u00fcrelerle uyan\u0131\u015f ya\u015farlar ama bunlar hi\u00e7bir zaman 1969 yaz\u0131ndaki kadar \u00e7arp\u0131c\u0131
olamaz. Uygulanan onca ila\u00e7 tedavisinin ba\u015far\u0131s\u0131z sonu\u00e7lanmas\u0131, hastalar\u0131n sebebi
bilinmeyen bir salg\u0131n y\u00fcz\u00fcnden y\u0131llarca d\u0131\u015f d\u00fcnyadan kopuk bir uyku halinde hayatlar\u0131na
devam etmeleri, edebiyat ve sineman\u0131n e\u015fli\u011finde y\u0131llar sonra bile bizler i\u00e7in salg\u0131n\u0131n gizemini
g\u00f6zler \u00f6n\u00fcne serer. Kim bilir belki de y\u0131llar sonra bu hastal\u0131\u011f\u0131n as\u0131l sebebi bilim insanlar\u0131
taraf\u0131ndan bulunur bizler de kitaplarda ve sinemada salg\u0131n\u0131n gizemini de\u011fil g\u00fcn y\u00fcz\u00fcne
\u00e7\u0131kan ger\u00e7eklerinin yans\u0131malar\u0131n\u0131 g\u00f6r\u00fcr\u00fcz.<\/p>\n\n\n\n![\"\"](\"https:\/\/blog.ulubat.org\/wp-content\/uploads\/2023\/12\/WhatsApp-Image-2023-12-05-at-23.15.00-3-2-1024x1024.jpeg\")
<\/h2>\n\n\n\n
https:\/\/www.indyturk.com\/node\/545476\/bi%CC%87li%CC%87m\/sandmandeki-gizemlisalg%C4%B1n-100-y%C4%B1l-%C3%B6nce-ger%C3%A7ekten-de-ya%C5%9Fanm%C4%B1%C5%9F
https:\/\/www.youtube.com\/watch?v=sa8lnbrD9FU&ab_channel=TVNETX
https:\/\/www.youtube.com\/watch?v=5lNVtUlroZc&t=4s&ab_channel=WellcomeLibrary<\/p>\n","protected":false},"excerpt":{"rendered":"