{"id":2397,"date":"2019-07-26T20:32:34","date_gmt":"2019-07-26T17:32:34","guid":{"rendered":"http:\/\/blog.ulubat.org\/?p=2397"},"modified":"2019-07-26T20:32:36","modified_gmt":"2019-07-26T17:32:36","slug":"bipolar-bozukluk","status":"publish","type":"post","link":"https:\/\/blog.ulubat.org\/index.php\/genel\/bipolar-bozukluk\/","title":{"rendered":"B\u0130POLAR BOZUKLUK"},"content":{"rendered":"\n

Bipolar bozukluk, hastalar\u0131 iki u\u00e7lu duygu durumuna s\u00fcr\u00fckleyen ve hayat\u0131 zorla\u015ft\u0131ran bir psikiyatrik bozukluktur.Tarihte ara\u015ft\u0131rmalar\u0131na \u00e7ok\u00e7a yer verilmi\u015f, zamanla yap\u0131lan ara\u015ft\u0131rmalarla bipolar bozukluk a\u00e7\u0131klanmaya \u00e7al\u0131\u015f\u0131lm\u0131\u015ft\u0131r. Babil, Eski M\u0131s\u0131r, \u0130brani ve \u00c7in k\u00fclt\u00fcrlerinde depresif (melankolik) ve manik durumlara ait betimlemelere rastlansa da, bu tan\u0131mlamalar\u0131 ilk kez sistematik \u015fekilde yapan ki\u015fi, M\u00d6 400\u2019de, Hipokrat olmu\u015ftur.\u00a0Hipokrat melankoliyi kara safran\u0131n beyin \u00fczerindeki etkileri sonucu ruhun kararmas\u0131 durumu \u015feklinde tan\u0131mlam\u0131\u015ft\u0131r. <\/p>\n\n\n\n

\"\"
Hipokrat
https:\/\/www.news-medical.net\/health\/Sepsis-History-(Italian).aspx<\/a> <\/figcaption><\/figure>\n\n\n\n

<\/p>\n\n\n\n

Kapadokya\u2019l\u0131 Aretaeus ise maninin temel belirtilerini tan\u0131mlam\u0131\u015f, bug\u00fcnk\u00fc mani kavram\u0131n\u0131 ortaya atm\u0131\u015ft\u0131r. Ayn\u0131 zamanda mani ve depresyonun ayn\u0131 hastal\u0131\u011f\u0131n iki farkl\u0131 g\u00f6r\u00fcn\u00fcm\u00fc oldu\u011funu belirtmi\u015ftir. Orta\u00e7a\u011f Avrupas\u0131\u2019nda ise psikolojik rahats\u0131zl\u0131klar \u015feytan\u0131n bedeni ele ge\u00e7irmesine dayanarak a\u00e7\u0131klanm\u0131\u015ft\u0131r. Bu da o d\u00f6nemi psikiyatri i\u00e7in karanl\u0131k bir d\u00f6nem haline getirmi\u015ftir. Bu d\u00f6nemde Avrupa\u2019n\u0131n aksine Arap d\u00fcnyas\u0131 eski Yunan metinlerini \u00e7evirerek psikiyatriye \u0131\u015f\u0131k tutmaya \u00e7al\u0131\u015fm\u0131\u015ft\u0131r. \u0130bni Sina bu d\u00f6nemde mani ve melankolinin ki\u015filik \u00f6zelliklerinden ve de spermlerdeki bozukluklardan etkilenebilece\u011fini belirterek genetik ge\u00e7i\u015fin psikiyatrik rahats\u0131zl\u0131klarda bir fakt\u00f6r olabilece\u011fini \u00f6ng\u00f6rm\u00fc\u015ft\u00fcr.<\/p>\n\n\n\n

16. ve 17. y\u00fczy\u0131llarda bilim alan\u0131nda Aretaeus\u2019un bak\u0131\u015f\na\u00e7\u0131s\u0131 ge\u00e7erli g\u00f6r\u00fclmekteydi.19. y\u00fczy\u0131lda ise Esquirol melankoliyle ili\u015fkili\nparanoid belirtilerin duygu durum bozuklu\u011fundan kaynaklanabilece\u011fini belirterek\nyeni bir perspektif sunan ilk psikiyatrist olmu\u015ftur.<\/p>\n\n\n\n

Bilim d\u00fcnyas\u0131 19. y\u00fczy\u0131lda hastal\u0131klar\u0131, daha farkl\u0131 bir yakla\u015f\u0131mla a\u00e7\u0131klanmaya ba\u015flam\u0131\u015ft\u0131. Bu d\u00f6nemde psikiyatrik hastal\u0131klar\u0131n nedeninin, beynin fizyolojik bozukluklar\u0131 oldu\u011fu g\u00f6r\u00fc\u015f\u00fc benimsendi.1851\u2019de bipolar bozukluk i\u00e7in \u00f6nemli bir noktaya gelindi. Falret, 1851\u2019de, manik, depresif ve s\u00fcresi belirsiz normal ara d\u00f6nemler (intervaller) \u015feklinde gidi\u015f g\u00f6steren ayr\u0131 bir hastal\u0131ktan s\u00f6z ederek, buna \u2018folie circulaire\u2019 ad\u0131n\u0131 verdi. B\u00f6ylece, modern bipolar bozukluk kavram\u0131n\u0131n temeli at\u0131lm\u0131\u015f bulunuyordu. <\/p>\n\n\n\n

\"\"
Emil Kraepelin
http:\/\/broughttolife.sciencemuseum.org.uk\/broughttolife\/people\/emilkraepelin<\/a> <\/figcaption><\/figure><\/div>\n\n\n\n

<\/p>\n\n\n\n

Bug\u00fcnk\u00fc bipolar bozukluk kavram\u0131n\u0131n babas\u0131 say\u0131labilecek Kraepelin ise 1896\u2019da endojen (i\u00e7 yap\u0131sal) psikozlar\u0131, dementia praecox (erken bunama) ve manik-depresif delilik olarak ikiye ay\u0131rd\u0131. T\u00fcm melankoli ve mani bi\u00e7imlerini \u201cmanik-depresif\u201d hastal\u0131k ba\u015fl\u0131\u011f\u0131nda birle\u015ftirdi, hastal\u0131\u011f\u0131n genetik ge\u00e7i\u015fli oldu\u011funu g\u00f6sterdi. Daha sonra Angst (1966) ve Perris (1966), unipolar depresyonun cinsiyet, genetik, gidi\u015f, hastal\u0131k \u00f6ncesi ki\u015filik yap\u0131s\u0131 ve hastal\u0131\u011f\u0131n ba\u015flama ya\u015f\u0131 gibi \u00e7e\u015fitli a\u00e7\u0131lardan, ger\u00e7ekten de bipolar bozukluktan farkl\u0131 bir hastal\u0131k oldu\u011funu g\u00f6sterdiler. B\u00f6ylece, unipolar depresyon \u2018depresif hastal\u0131k\u2019 \u015feklinde, bipolar bozukluktan ayr\u0131ld\u0131. K\u0131saca unipolar depresyonu a\u00e7\u0131klarsak: Bir ki\u015fi hayat\u0131nda ilk kez depresyon ge\u00e7iriyorsa bu unipolar depresyon olabilir.<\/p>\n\n\n\n

Modern t\u0131bb\u0131n geli\u015fmesiyle \u015fu an bipolar bozukluk hakk\u0131nda daha \u00e7ok bilgi sahibiyiz.Yap\u0131lan yeni ara\u015ft\u0131rmalar bipolar bozuklu\u011fun i\u015fleyi\u015fini daha detayl\u0131 bir \u015fekilde a\u00e7\u0131kl\u0131yor. <\/p>\n\n\n\n

\"\"
Bipolar bozuklu\u011fu anlatan bir ill\u00fctrasyon
https:\/\/www.depam.com\/2018\/06\/07\/bipolar-bozukluk-roportaji\/<\/a> <\/figcaption><\/figure>\n\n\n\n

<\/p>\n\n\n\n

Bipolar bozukluk iki d\u00f6nemi bulunan bir hastal\u0131kt\u0131r. Bunlardan biri mani di\u011feri ise depresyon d\u00f6nemidir. Mani ve depresyon d\u00f6nemleri d\u0131\u015f\u0131nda hasta normale d\u00f6ner. Normale d\u00f6n\u00fclen zamana yat\u0131\u015fma d\u00f6nemi denir.<\/p>\n\n\n\n

Bipolar bozukluk d\u00f6nemlerinden mani veya ta\u015fk\u0131nl\u0131k d\u00f6nemi\nduygu durumun \u00e7ok y\u00fckseldi\u011fi, hastan\u0131n a\u015f\u0131r\u0131 co\u015fkulu oldu\u011fu d\u00f6nemdir. Bu\nd\u00f6nemde hastada abart\u0131l\u0131 d\u00fc\u015f\u00fcnceler, kendini oldu\u011fundan \u00e7ok daha y\u00fcksekte hissetme,\nb\u00fcy\u00fckl\u00fck d\u00fc\u015f\u00fcnceleri, a\u015f\u0131r\u0131 enerjik olma, bir fikirden di\u011ferine atlama,k\u0131\u015fk\u0131rt\u0131c\u0131,\nm\u00fcdahaleci veya sald\u0131rgan davran\u0131\u015f,uykuya ihtiya\u00e7 duymama, d\u00fc\u015f\u00fcnmeden hareket\netme, heyecanl\u0131 ve e\u011flenceli i\u015flere tehlikeleri g\u00f6z ard\u0131 ederek at\u0131lma g\u00f6r\u00fclen\nbelirtilere \u00f6rnektir.<\/p>\n\n\n\n

Di\u011fer yandan depresyon d\u00f6nemi ise yukar\u0131da yaz\u0131lan\ndurumun tam tersidir. Depresyonda ise hastada mutsuzluk, karamsarl\u0131k, umutsuzluk,\n\u00f6zg\u00fcvende azalma, de\u011fersiz hissetme, abart\u0131l\u0131 su\u00e7luluk veya pi\u015fmanl\u0131k\nduygular\u0131, eskiden zevk ald\u0131\u011f\u0131 faaliyetlerden zevk alamama, i\u015ftahs\u0131zl\u0131k veya\nuykusuzluk gibi de\u011fi\u015fiklikler, \u00f6l\u00fcm ve intihar d\u00fc\u015f\u00fcnceleri, hat\u0131rlama ya da\nkarar vermede zorluk, bedeninde nedeni a\u00e7\u0131klanamayan a\u011fr\u0131lar g\u00f6r\u00fcl\u00fcr.<\/p>\n\n\n\n

Mani ve depresyon d\u00f6nemlerinin s\u00fcreleri ki\u015fiden ki\u015fiye de\u011fi\u015febilir. Bir ki\u015fi depresyonda, mani d\u00f6neminden \u00e7ok daha fazla zaman ge\u00e7irebilir.<\/p>\n\n\n\n

Bipolar bozukluk toplumlar aras\u0131 farkl\u0131l\u0131k g\u00f6stermemekte ve ortalama olarak %2-3 civar\u0131nda g\u00f6r\u00fclmektedir. Erkek kad\u0131n oran\u0131 e\u015fittir ve ortalama ba\u015flang\u0131\u00e7 ya\u015f\u0131 20\u201325 aras\u0131ndad\u0131r.<\/p>\n\n\n\n

Peki bipolar bozukluk neden g\u00f6r\u00fcl\u00fcr? Genetik\nkomponentleri var m\u0131d\u0131r? Ya\u015fam standartlar\u0131, \u00e7ocukluk \u00e7a\u011f\u0131 travmalar\u0131,\nal\u0131\u015fkanl\u0131klar ve d\u0131\u015f etkenler ne \u00f6l\u00e7\u00fcde BD\u2019ye neden olur? <\/p>\n\n\n\n

Genetik Fakt\u00f6rler<\/strong><\/p>\n\n\n\n

MIT’deki Picower \u00d6\u011frenme ve Bellek Enstit\u00fcs\u00fc’ndeki ara\u015ft\u0131rmac\u0131lar taraf\u0131ndan yap\u0131lan bir \u00e7al\u0131\u015fma, CPG2 proteininin bipolar bozuklu\u011fu olan ki\u015filerin (BD) beyinlerinde \u00f6nemli \u00f6l\u00e7\u00fcde daha az oldu\u011funu g\u00f6sterdi ve proteini kodlayan SYNE1 genindeki spesifik mutasyonlar\u0131n, proteinin \u00fcretimine zarar verdi\u011fini ortaya koydu.<\/p>\n\n\n\n

MIT’nin Biyoloji ve Beyin ve Bili\u015fsel Bilimler\nb\u00f6l\u00fcmlerinde profes\u00f6r olan Elly Nedivi ve eski postdoc Mette Rathje\nba\u015fkanl\u0131\u011f\u0131ndaki \u00e7al\u0131\u015fma, bipolar bozuklu\u011fu olan hastalar\u0131n genetik varyasyonlar\u0131n\u0131n,\nbeyindeki sinirsel devre ba\u011flant\u0131lar\u0131(snapslar) \u00fczerindeki i\u015flev bozuklu\u011funa\nnas\u0131l yol a\u00e7abilece\u011fini g\u00f6steriyor. Ara\u015ft\u0131rmac\u0131lar SYNE1 geni \u00fczerindeki CPG2\ngeni varyasyonlar\u0131n\u0131n bipolar bozuklu\u011fun \u201cnedeni\u201d de\u011fil, hastal\u0131k olu\u015fumu\n\u00fczerinde duyarl\u0131l\u0131\u011f\u0131 artt\u0131r\u0131c\u0131 bir etken oldu\u011funu \u00f6ne s\u00fcr\u00fcyorlar. \u00d6nemli bir\ndisfonksiyon elde edebilmek i\u00e7in bazen tek gen varyant\u0131n\u0131n yeterli olmad\u0131\u011f\u0131n\u0131\ns\u00f6yl\u00fcyorlar.<\/p>\n\n\n\n

\"\"
Gen: biyolojik k\u00f6klerimiz
http:\/\/discovermagazine.com\/2014\/jan-feb\/45-id-for-genetic-adam<\/a> <\/figcaption><\/figure>\n\n\n\n

<\/p>\n\n\n\n

Peki nedir bu CPRG2?<\/strong><\/p>\n\n\n\n

CPRG2 sinirsel uyar\u0131mlarla sal\u0131nan Glutamat\nn\u00f6rotransmiterinin resept\u00f6rleri i\u00e7in d\u00fczenleyici bir proteindir. Beyin\ndevrelerinde ba\u011flant\u0131lar\u0131n g\u00fcc\u00fcn\u00fc mod\u00fcle etmek i\u00e7in anahtar bir mekanizmad\u0131r.<\/p>\n\n\n\n

Yeni \u00e7al\u0131\u015fma i\u00e7in Rathje, CPG2’nin bipolar hastalar\u0131nda nas\u0131l farkl\u0131 olabilece\u011fini ara\u015ft\u0131rmak ad\u0131na postmortem beyin dokusu \u00f6rneklerini toplad\u0131. \u00d6rnekler, bipolar bozukluk tan\u0131s\u0131 konmu\u015f insanlardan, depresyon veya \u015fizofreni gibi komorbid semptomlar\u0131 olan n\u00f6ropsikiyatrik bozukluklardan ve bu hastal\u0131klardan hi\u00e7birine sahip olmayan insanlardan olu\u015fmaktayd\u0131. Sadece bipolar bozuklu\u011fu olan insanlardan al\u0131nan \u00f6rneklerde CPG2 anlaml\u0131 derecede d\u00fc\u015f\u00fckt\u00fc. Di\u011fer anahtar sinaptik proteinler bipolar hastalarda benzersiz olarak daha d\u00fc\u015f\u00fck de\u011fildi. Bu ba\u011flamda ara\u015ft\u0131rmac\u0131lar: \u201cBulgular\u0131m\u0131z d\u00fc\u015f\u00fck CPG2 seviyeleri ile \u015fizofreni veya maj\u00f6r depresyon hastalar\u0131 ile payla\u015f\u0131lmayan BD insidans\u0131 aras\u0131nda \u00f6zel bir ili\u015fki oldu\u011funu g\u00f6steriyor.\u201d a\u00e7\u0131klamas\u0131nda bulundu.<\/p>\n\n\n\n

Ara\u015ft\u0131rmalar\u0131n g\u00f6sterdi\u011fi \u00fczere bipolar bozukluk genetik\nfakt\u00f6rlerden etkilenen, yatk\u0131nl\u0131\u011f\u0131n g\u00f6r\u00fclebildi\u011fi psikolojik bir bozukluktur.<\/p>\n\n\n\n

\u00c7ocukluk Travmalar\u0131<\/strong><\/p>\n\n\n\n

\u00c7ocukluk \u00e7a\u011f\u0131 travmalar\u0131 zaman i\u00e7inde klinik a\u00e7\u0131dan bir\u00e7ok tabloya neden olabilecek risk fakt\u00f6rlerinden biridir.Bu tablolardan biri de bipolar bozukluk geli\u015fimi tablosudur. \u00c7ocukluk \u00e7a\u011f\u0131nda travma maruziyeti, ki\u015finin ya\u015fam\u0131 boyunca olaylarla ba\u015fa \u00e7\u0131kma yetene\u011fini zedeleyebilir, bili\u015fsel i\u015fleyi\u015fe zarar verebilir. \u00c7ocukluk \u00e7a\u011f\u0131 travmas\u0131, bozuklu\u011fun ba\u015flang\u0131c\u0131ndaki ya\u015f\u0131 azaltmak ya da artt\u0131rmak i\u00e7in birka\u00e7 farkl\u0131 biyolojik yola (Hipotalamik – hipofiz – adrenal (HPA) ekseni, serotonerjik ge\u00e7i\u015f, n\u00f6roplastisite, ba\u011f\u0131\u015f\u0131kl\u0131k, kalsiyum sinyallemesi) ait \u00e7e\u015fitli genlerle etkile\u015fime girer.Ayn\u0131 zamanda bipolar bozuklu\u011fun olu\u015fumunda \u00e7ocukluk \u00e7a\u011f\u0131 travmas\u0131n\u0131n mekanizmas\u0131na ek epigenetik fakt\u00f6rler de rol alabilir. <\/p>\n\n\n\n

\"\"
\u00c7ocukluk travmalar\u0131na son vermek hepimizin elinde!
https:\/\/crsh.com\/Blog\/You-Belong-to-Me-The-lasting-trauma-of-male-survivors-of-childhood-sexual-abuse<\/a> <\/figcaption><\/figure>\n\n\n\n

<\/p>\n\n\n\n

DS\u00d6 (D\u00fcnya Sa\u011fl\u0131k \u00d6rg\u00fct\u00fc), t\u00fcm yeti\u015fkinlerin d\u00f6rtte birinin \u00e7ocuk olarak cinsel tacize u\u011frad\u0131\u011f\u0131n\u0131, be\u015f kad\u0131ndan birinin ve 13 erkekten birinin \u00e7ocuk tacizine maruz kald\u0131\u011f\u0131n\u0131 bildirdi\u011fini tahmin etmektedir (DS\u00d6, K\u00fct\u00fcphane Yay\u0131nc\u0131l\u0131k Verileri\u00a02006<\/a>).\u00a0Ciddi zihinsel bozukluklardan muzdarip olan bireylerde, \u00e7ocukluk \u00e7a\u011f\u0131 travmas\u0131 \u00e7ok daha y\u00fcksek oranda bildirilmektedir.\u00a0<\/p>\n\n\n\n

\u00c7ocukluk \u00c7a\u011f\u0131 Travma Anketi(CTQ) kullanarak yap\u0131lan bir vaka kontrol \u00e7al\u0131\u015fmas\u0131nda, \u00e7oklu travmalar\u0131n bipolar bozuklu\u011fu olan hastalarda kontrollere g\u00f6re daha s\u0131k oldu\u011fu g\u00f6sterilmektedir. Bu ve benzeri \u00e7al\u0131\u015fmalar sonunda \u00fc\u00e7 sonu\u00e7 ortaya \u00e7\u0131km\u0131\u015ft\u0131r:<\/p>\n\n\n\n

1) \u00e7ocukluk \u00e7a\u011f\u0131 travmas\u0131 ile bipolar bozukluk ba\u015flang\u0131c\u0131 ve erken ya\u015f aras\u0131ndaki ili\u015fki<\/p>\n\n\n\n

2) intihar giri\u015fimi riskinin artmas\u0131<\/p>\n\n\n\n

3) komorbid madde k\u00f6t\u00fcye kullan\u0131m\u0131.<\/p>\n\n\n\n

HHV-6 ve Bipolar Bozukluk<\/strong><\/p>\n\n\n\n

\"\"
HHV-6 vir\u00fcs\u00fcn\u00fcn bir g\u00f6r\u00fcnt\u00fcs\u00fc
https:\/\/www.wtvy.com\/wrgx\/content\/news\/Roseola-and-its-effects-on-children-437602273.html<\/a> <\/figcaption><\/figure>\n\n\n\n

<\/p>\n\n\n\n

W\u00fcrzburg \u00dcniversitesi Viroloji ve \u0130mm\u00fcnobiyoloji Enstit\u00fcs\u00fc’nden bilim adamlar\u0131 ve ABD’li meslekta\u015flar\u0131 psikiyatrik bozuklu\u011fu bulunan hastalarda insan serebellumunun Purkinje h\u00fccrelerinde HHV-6 aktif enfeksiyonu bulduklar\u0131n\u0131 ve bu hastalar\u0131n bipolar ve maj\u00f6r depresif bozukluk hastalar\u0131 oldu\u011funu belirtiyorlar. Bu anlamda HHV-6\u2019n\u0131n bipolar bozuklukta etken olabilece\u011fini d\u00fc\u015f\u00fcn\u00fcyorlar. Sonu\u00e7lar, ilk kez HHV-6 vir\u00fcslerinin n\u00f6ronlar\u0131 enfekte edebildi\u011fini ve muhtemelen duygudurum bozuklu\u011funa yol a\u00e7an bili\u015fsel rahats\u0131zl\u0131klara neden oldu\u011funu g\u00f6steriyor.<\/p>\n\n\n\n

 Bipolar\nBozuklukta Yeme Bozukluklar\u0131<\/strong><\/p>\n\n\n\n

Yap\u0131lan incelemelerde Yeme bozukluklar\u0131n\u0131n (ED), bipolar\nbozuklukla (BD) ortaya \u00e7\u0131kt\u0131\u011f\u0131 belirtilmektedir, ancak ilave komorbiditeler,\nklinik korelasyonlar ve her ikisi i\u00e7in ortak olan ki\u015filik fakt\u00f6rleri aras\u0131ndaki\nili\u015fkilerin b\u00fcy\u00fck oranda bilinmedi\u011fi g\u00f6r\u00fclmektedir. Fakat BD’li hastalar ED,\nanksiyete bozukluklar\u0131 ve alkol kullan\u0131m bozukluklar\u0131 a\u00e7\u0131s\u0131ndan d\u00fczenli olarak\ntaranmal\u0131d\u0131r.<\/p>\n\n\n\n

Bipolar Bozukluk Tan\u0131s\u0131nda Yeni\nY\u00f6ntemler<\/strong><\/p>\n\n\n\n

Bipolar bozukluk hastal\u0131\u011f\u0131n gidi\u015fat\u0131, semptomlar\u0131 ve aile \u00f6yk\u00fcs\u00fc dikkate al\u0131narak tan\u0131 koyulan bir psikiyatrik hastal\u0131k. G\u00fcn\u00fcm\u00fczde yeni ara\u015ft\u0131rmalarla daha kesin ve erken te\u015fhis y\u00f6ntemleri bipolar bozuklu\u011fa daha kapsaml\u0131 yakla\u015fmam\u0131za yard\u0131m ediyor.<\/p>\n\n\n\n

Bipolar bozuklu\u011fa sahip bir aile \u00fcyesine sahip olmak, genetik bile\u015fenleri gere\u011fince di\u011fer aile fertlerini risk alt\u0131na sokar.Bu nedenle erken te\u015fhis ve bipolar bozuklu\u011fun di\u011fer psikiyatrik hastal\u0131klardan ayr\u0131m\u0131 i\u00e7in yeni y\u00f6ntemler ara\u015ft\u0131r\u0131l\u0131yor. Yap\u0131lan ara\u015ft\u0131rmalarda geli\u015ftirilen y\u00f6ntemle potansiyel hasta adaylar\u0131n\u0131n bireysel tespiti hedefleniyor. \u00a0Dr. Oliveira : \u201cBu bulgular, erken d\u00f6nem terap\u00f6tik(tedavi edici) m\u00fcdahalelerin geli\u015fimine ve se\u00e7imine rehberlik etmek, bu savunmas\u0131z bireylerde hastal\u0131kla ili\u015fkili \u00f6nemli sosyal maliyetleri ve zararl\u0131 sonu\u00e7lar\u0131 azaltmak i\u00e7in potansiyel olarak kullan\u0131labilir\u201d a\u00e7\u0131klamas\u0131nda bulundu.<\/p>\n\n\n\n

N\u00f6rog\u00f6r\u00fcnt\u00fcleme kullan\u0131larak tan\u0131ya ula\u015fmay\u0131 sa\u011flayan bu y\u00f6ntem bipolar bozuklu\u011fun mani d\u00f6nemini dikkate alarak toplanan verilere g\u00f6re bir risk tablosu olu\u015fturuyor. Riski \u00f6ng\u00f6rebilmek ad\u0131na mani d\u00f6neminde potansiyel \u00f6d\u00fcllere y\u00f6nelik d\u00fcrt\u00fcsel tepkiler\u00a0izleniyor. B\u00f6ylelikle geli\u015ftirilen bu y\u00f6ntem\u00a0hen\u00fcz bozuklu\u011fu geli\u015ftirmemi\u015f gen\u00e7 eri\u015fkinlerde mani semptomunun ciddiyeti \u00f6ng\u00f6r\u00fclebiliyor.<\/p>\n\n\n\n

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N\u00f6rog\u00f6r\u00fcnt\u00fclemede amigdala etkinli\u011fini g\u00f6r\u00fcyoruz.
https:\/\/neurosciencenews.com\/neuroimaging-bipolar-depression-9792\/<\/a> <\/figcaption><\/figure>\n\n\n\n

<\/p>\n\n\n\n

Bir di\u011fer y\u00f6ntem ise Westmead Enstit\u00fcs\u00fc\u2019n\u00fcn haz\u0131rlad\u0131\u011f\u0131 \u00e7al\u0131\u015fmaya dayanmakta.<\/em> Bipolar bozuklu\u011fun yanl\u0131\u015f tan\u0131 almas\u0131n\u0131 \u00f6nlemek amac\u0131yla y\u00fcr\u00fct\u00fclen bu ara\u015ft\u0131rma sonucunda depresyon ve bipolar bozuklu\u011fun ay\u0131r\u0131c\u0131 tan\u0131s\u0131nda kullan\u0131lacak bir n\u00f6rog\u00f6r\u00fcnt\u00fcleme y\u00f6ntemi geli\u015ftirildi.G\u00fcn\u00fcm\u00fczde bipolar bozuklu\u011fu olan hastalar\u0131n yakla\u015f\u0131k% 60’\u0131 ba\u015flang\u0131\u00e7ta maj\u00f6r depresif bozukluk olarak yanl\u0131\u015f tan\u0131 almaktad\u0131r. Bunun \u00f6n\u00fcne ge\u00e7mek ad\u0131na ara\u015ft\u0131rma ekibi, duygular\u0131 i\u015flemede kilit rol oynayan bir dizi n\u00f6ron olan amigdalan\u0131n bir hastan\u0131n \u00f6fke, korku, \u00fcz\u00fcnt\u00fc, i\u011frenme ve mutluluk gibi y\u00fcz ifadelerini nas\u0131l i\u015fledi\u011fini g\u00f6rmek i\u00e7in karma\u015f\u0131k MRI taramas\u0131n\u0131 kulland\u0131. Depresyon hastalar\u0131n\u0131n ve bipolar bozuklu\u011fu olan hastalar\u0131n amigdalalar\u0131n\u0131n farkl\u0131 tepkiler verdi\u011fi g\u00f6zlendi. Bipolar bozuklu\u011fu olan ki\u015filerde, amigdalan\u0131n sol taraf\u0131 daha az aktif \u00a0ve beynin di\u011fer b\u00f6l\u00fcmleriyle depresyonlu insanlardan daha az ba\u011flant\u0131ya sahip oldu\u011fu ortaya \u00e7\u0131kt\u0131.Bu \u00e7al\u0131\u015fmadan elde edilen bulgular, bu ayr\u0131m\u0131n yap\u0131lmas\u0131nda% 80 kesinli\u011fe sahip.Bu derece bir kesinlikle benzer sempromlara yol a\u00e7abilecek iki hastal\u0131\u011f\u0131n yanl\u0131\u015f tan\u0131yla hasta i\u00e7in k\u00f6t\u00fc bir senaryoya d\u00f6n\u00fc\u015fmesi engellenmeye \u00e7al\u0131\u015f\u0131lacak.<\/p>\n\n\n\n

Bipolar Bozuklu\u011fun Tedavi\nY\u00f6ntemleri<\/strong><\/p>\n\n\n\n

Bipolar bozuklu\u011fun tedavisi, depresyon ve mani ataklar\u0131n\u0131n say\u0131s\u0131n\u0131 ve \u015fiddetini belirgin \u00f6l\u00e7\u00fcde azaltmay\u0131 ve g\u00fcnl\u00fck ya\u015fam\u0131n kalitesini artt\u0131rmay\u0131 ama\u00e7lar. Bu ama\u00e7la Lityum, antikonv\u00fclsan ve antidepresan ila\u00e7lar kullan\u0131l\u0131r.Bu s\u00fcre\u00e7te psikoterapi ve psikoe\u011fitim tedavinin bir par\u00e7as\u0131d\u0131r. Ancak \u00a0<\/strong>art\u0131k ruh hali semptomlar\u0131n\u0131 ve hastal\u0131kla ili\u015fkili zay\u0131flat\u0131c\u0131 t\u0131bbi y\u00fck\u00fc azaltmak i\u00e7in ek tedavilere ihtiya\u00e7 vard\u0131r. \u00d6rne\u011fin egzersizin, bipolar bozuklu\u011fu bulunan hastalar\u0131n ruh halini \u00f6nemli \u00f6l\u00e7\u00fcde iyile\u015ftirdi\u011fi tespit edildi. <\/strong><\/p>\n\n\n\n

\"\"
Egzersiz bir\u00e7ok hastal\u0131k gibi bipolar bozukluk i\u00e7in de faydal\u0131 bir ara\u00e7t\u0131r.
https:\/\/nimaltecnologia.com.br\/serie-06-dicas-de-treino-de-corrida\/<\/a> <\/figcaption><\/figure>\n\n\n\n

<\/p>\n\n\n\n

Bir di\u011fer tedavi se\u00e7eneklerinden biri de Beslenme, Egzersiz ve Sa\u011fl\u0131kl\u0131 Ya\u015fam Tedavisi (NEW Tx)\u2019dir. Beslenme, Egzersiz ve Sa\u011fl\u0131kl\u0131 Ya\u015fam Tedavisi (NEW Tx) \u00f6zellikle kilo problemi ve bipolar bozuklu\u011fu olan hastalarda uygulanabilir ve ruh hali semptomlar\u0131n\u0131 iyile\u015ftirilebilme potansiyeli oldu\u011fu ortaya kondu. <\/p>\n\n\n\n

Geli\u015ftirilen y\u00f6ntemlerle, kapsaml\u0131 tedavi olanaklar\u0131 ve bireyselle\u015ftirilmi\u015f bir izlem ile bipolar bozuklu\u011fu olan hastalar\u0131n g\u00fcnl\u00fck hayata kat\u0131lmas\u0131 ve ataklar\u0131n\u0131n hafiflemesi hedefleniyor.<\/p>\n\n\n\n

D\u00fcnya Bipolar G\u00fcn\u00fc<\/strong><\/p>\n\n\n\n

Ya\u015fam \u00f6yk\u00fcs\u00fc incelenerek bipolar bozukluk tan\u0131s\u0131 alan \u00fcnl\u00fc ressam Van Gogh\u2019un do\u011fum g\u00fcn\u00fc 30 Mart, 2014\u2019ten bu yana D\u00fcnya Bipolar G\u00fcn\u00fc olarak kutlan\u0131yor. B\u00f6ylelikle bipolar bozukluk i\u00e7in fark\u0131ndal\u0131k yaratmak temel ama\u00e7. <\/p>\n\n\n\n

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https:\/\/www.sheilds.org\/world-bipolar-day-2017\/<\/a> <\/figcaption><\/figure>\n\n\n\n

<\/p>\n\n\n\n

Bipolar bozukluk ciddi ve hayat\u0131 b\u00fcy\u00fck \u00f6l\u00e7\u00fcde zorla\u015ft\u0131ran psikiyatrik bir hastal\u0131kt\u0131r. Bu nedenle tedavi olanaklar\u0131n\u0131n ve te\u015fhis, izlem s\u00fcre\u00e7lerinin bir\u00e7ok kesimden hastaya ula\u015fabilmesi, intihar d\u00fc\u015f\u00fcncelerine s\u00fcr\u00fckleyebilecek bir depresyon d\u00f6nemi de i\u00e7eren bu hastal\u0131k i\u00e7in elzemdir. \u00c7ok y\u00f6nl\u00fc bir tedaviyle ve fark\u0131ndal\u0131kla bipolar bozuklu\u011fun hayat\u0131n\u0131za m\u00fcdahelesini en aza indirebilirsiniz. <\/p>\n\n\n\n

Not:<\/strong> Yanl\u0131\u015f\nbilgilere internet \u00fczerinden ula\u015fmak ve kendi kendinize te\u015fhis koymak, varsa\nhastal\u0131\u011f\u0131n\u0131z\u0131n seyrini k\u00f6t\u00fc etkileyecek, yoksa da sizi bo\u015fu bo\u015funa endi\u015feye\ns\u00fcr\u00fckleyecektir. Hasta oldu\u011funuzda \u015f\u00fcphelendi\u011finiz durumlarda doktorunuza\ndan\u0131\u015f\u0131n. 😊<\/p>\n\n\n\n

KAYNAK\u00c7A:<\/strong><\/p>\n\n\n\n

http:\/\/www.psikiyatri.org.tr\/halka-yonelik\/22\/bipolar-bozukluk-ikiuclu-bozukluk-manik-depresif-hastalik<\/a><\/p>\n\n\n\n

http:\/\/www.psikiyatri.org.tr\/halka-yonelik\/22\/bipolar-bozukluk-ikiuclu-bozukluk-manik-depresif-hastalik<\/a><\/p>\n\n\n\n

https:\/\/journalbipolardisorders.springeropen.com\/articles\/10.1186\/2194-7511-1-24<\/a><\/p>\n\n\n\n

https:\/\/journalbipolardisorders.springeropen.com\/articles\/10.1186\/s40345-015-0042-0<\/a><\/p>\n\n\n\n

https:\/\/journalbipolardisorders.springeropen.com\/articles\/10.1186\/s40345-017-0078-4<\/a><\/p>\n\n\n\n

https:\/\/neurosciencenews.com\/bipolar-genetics-10591\/<\/a><\/p>\n\n\n\n

https:\/\/neurosciencenews.com\/neuroimaging-bipolar-depression-9792\/<\/a><\/p>\n\n\n\n

https:\/\/neurosciencenews.com\/brain-activation-bipolar-14220\/<\/a><\/p>\n\n\n\n

https:\/\/neurosciencenews.com\/herpes-virus-depression-bipolar-11025\/<\/a><\/p>\n\n\n\n

https:\/\/www.psychologytoday.com\/us\/basics\/bipolar-disorder<\/a><\/p>\n\n\n\n

http:\/\/www.psikiyatri.org.tr\/1241\/dunya-bipolar-iki-uclu-gunu-tanitimi<\/a><\/p>\n\n\n\n

http:\/\/www.olcayyazici.com.tr\/hastalik\/tarihce\/3\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Bipolar bozukluk, hastalar\u0131 iki u\u00e7lu duygu durumuna s\u00fcr\u00fckleyen ve hayat\u0131 zorla\u015ft\u0131ran bir psikiyatrik bozukluktur.Tarihte ara\u015ft\u0131rmalar\u0131na \u00e7ok\u00e7a yer verilmi\u015f, zamanla yap\u0131lan<\/p>\n","protected":false},"author":156,"featured_media":2441,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[1],"tags":[],"acf":[],"views":2377,"_links":{"self":[{"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/posts\/2397"}],"collection":[{"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/users\/156"}],"replies":[{"embeddable":true,"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/comments?post=2397"}],"version-history":[{"count":7,"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/posts\/2397\/revisions"}],"predecessor-version":[{"id":2440,"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/posts\/2397\/revisions\/2440"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/media\/2441"}],"wp:attachment":[{"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/media?parent=2397"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/categories?post=2397"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/tags?post=2397"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}