{"id":5194,"date":"2020-03-24T15:24:45","date_gmt":"2020-03-24T12:24:45","guid":{"rendered":"http:\/\/blog.ulubat.org\/?p=5194"},"modified":"2020-03-24T15:31:57","modified_gmt":"2020-03-24T12:31:57","slug":"tarihin-akisinda-yuz-nakli-devrimi","status":"publish","type":"post","link":"https:\/\/blog.ulubat.org\/index.php\/genel\/tarihin-akisinda-yuz-nakli-devrimi\/","title":{"rendered":"TAR\u0130H\u0130N AKI\u015eINDA Y\u00dcZ NAKL\u0130 DEVR\u0130M\u0130"},"content":{"rendered":"\n
\"y\u00fcz
https:\/\/im.haberturk.com\/2012\/01\/29\/ver1340620925\/710573_detay.jpg<\/figcaption><\/figure>\n\n\n\n

Organ\nve doku nakli, i\u015flevini kaybetmi\u015f organ\u0131n yerine  canl\u0131 bir don\u00f6rden (verici) veyahut beyin\n\u00f6l\u00fcm\u00fc ger\u00e7ekle\u015fmi\u015f ki\u015fiden al\u0131nan sa\u011flam organ\u0131n implante edilmesidir.G\u00fcn\u00fcm\u00fczde\nb\u00f6brek, karaci\u011fer, kalp, akci\u011fer,\npankreas ve ince barsak , kalp kapa\u011f\u0131, kornea, kemik, kemik ili\u011fi ve deri gibi\nbir \u00e7ok organ ve dokunun nakli yap\u0131lmaktad\u0131r. Biliyoruz ki ya\u015fam\u0131n insanlar aras\u0131nda\nolu\u015fturdu\u011fu en mutualist ili\u015fkilerden biri olan organ ve doku transplantasyonu\ngerek duygusal gerekse fizyolojik a\u00e7\u0131dan don\u00f6r ve al\u0131c\u0131 aras\u0131nda soyut bir ba\u011f\nolu\u015fturmakta.Hasta ki\u015finin ya\u015fam kalitesinin artmas\u0131 ve beyin \u00f6l\u00fcm\u00fc ger\u00e7ekle\u015fen\nbireyin organlar\u0131n\u0131n ya\u015fat\u0131lmas\u0131 amac\u0131yla ger\u00e7ekle\u015ftirilen bu nakiller \u00e7ok\ndonan\u0131ml\u0131 cerrahi ekiplerle b\u00fcy\u00fck bir titizlikle ger\u00e7ekle\u015ftiriliyor.Ancak\neminin ki \u00e7ok b\u00fcy\u00fck bir \u00e7o\u011funlu\u011fumuz organ nakli uygulamas\u0131n\u0131 en \u00e7ok \u00fclkemizde\ngerekle\u015ftirilen ilk Y\u00dcZ NAKL\u0130 ile birlikte sorgulamaya ve ara\u015ft\u0131rmaya\nba\u015flad\u0131k.Evet kabul ediyorum ger\u00e7ekten \u00e7ok etkileyici ve \u015fa\u015f\u0131rt\u0131c\u0131 bir durumdu.Bize\nfilmleri an\u0131msatacak derecede bir olguydu .Ben de t\u00fcm bunlardan yola \u00e7\u0131karak\nmerak etti\u011fimiz ve mekanizmas\u0131n\u0131 anlayamad\u0131\u011f\u0131m\u0131z t\u0131p d\u00fcnyas\u0131ndaki en ilgin\u00e7\nmedikal i\u015flemlerden biri hatta en ilginci olan y\u00fcz nakli operasyonlar\u0131n\u0131n\ni\u00e7eri\u011fiyle ilgili size cok geni\u015f kapsaml\u0131 bir yaz\u0131 yazmaya karar verdim.Bir\nyaz\u0131 serisi \u015feklinde yay\u0131mlayaca\u011f\u0131m konuyu 3 b\u00f6l\u00fcmde sizlere aktaraca\u011f\u0131m ve ilk\nb\u00f6l\u00fcm\u00fcnde y\u00fcz naklinin tarihinden,bu noktalara  nas\u0131l ve ne \u015fekilde gelindi\u011finden\nbahsedece\u011fim.<\/strong><\/p>\n\n\n\n

Homojen bir yap\u0131ya sahip olmay\u0131p farkl\u0131\/\u00e7oklu doku ve organ par\u00e7alar\u0131ndan meydana gelen; di\u011fer bir ifadeyle \u201ckompozit\u201d  doku nakli t\u00fcrlerinden biri olan y\u00fcz nakli di\u011fer transplantasyonlardan bu y\u00f6n\u00fcyle ayr\u0131lsa da esas fark\u0131 psikolojik ve davran\u0131\u015fsal olarak olu\u015fturuyor.\u00c7\u00fcnk\u00fc bir insan\u0131 m\u00fcmk\u00fcn olmad\u0131\u011f\u0131 halde  organs\u0131z d\u00fc\u015f\u00fcnebilir ve betimleyebiliriz ancak bu y\u00fcz i\u00e7in ge\u00e7erli de\u011fildir.\u00c7\u00fcnk\u00fc insanlar y\u00fczleriyle vard\u0131r ve bir insan t\u00fcr\u00fcn\u00fc asla y\u00fcz\u00fc olmadan hayal edemezsiniz.Y\u00fczler ve mimikler i\u00e7 d\u00fcnyan\u0131n ve bilin\u00e7 alt\u0131nda olu\u015fturdu\u011fu birikimin d\u0131\u015fa vurumu ve d\u0131\u015f d\u00fcnyan\u0131n beyin derinli\u011finde alg\u0131lanma bi\u00e7imidir.Bu y\u00fczden y\u00fcz sadece bir organ de\u011fil ayn\u0131 zamanda sosyolojik bir tamamlay\u0131c\u0131d\u0131r. Asl\u0131nda bak\u0131ld\u0131\u011f\u0131nda organ nakli fikri \u00e7ok eski devirlere dayan\u0131yor. Hindistan’da eski devirlerde su\u00e7lular\u0131n burunlar\u0131 kesilir ve Hint cerrahlar, kesik burunlar\u0131 tamir ederlerdi.Hastan\u0131n kolundan ince bir deri ve derialt\u0131 ya\u011f dokusu par\u00e7as\u0131 kald\u0131r\u0131larak buruna tutturulur ve deri par\u00e7as\u0131, y\u00fczdeki kan deveran\u0131 ile ahenk temin etti\u011finde, kolla ba\u011flant\u0131s\u0131 kesilirdi. On sekizinci y\u00fczy\u0131lda bir \u0130talyan cerrah olan Baronio, dikkatle yap\u0131lacak olan bir ameliyat sonucunda bir hastan\u0131n v\u00fccudundan al\u0131nan deri par\u00e7alar\u0131n\u0131n ayn\u0131 insana nakledilebilece\u011fini de s\u00f6ylemi\u015ftir.\u00dczerinden y\u0131llar ge\u00e7tikten sonra ilk kez b\u00fct\u00fcn\u00fcyle bir y\u00fcz\u00fcn dikilmesi ger\u00e7ekle\u015fmi\u015ftir.Hindistanda 19  ya\u015f\u0131ndaki Sandeep Kaur \u2018un harmana sa\u00e7\u0131n\u0131 kapt\u0131rmas\u0131yla y\u00fcz\u00fcn\u00fcn b\u00fct\u00fcne yak\u0131n soyulmu\u015ftur ve soyulan par\u00e7alar sa\u011fl\u0131k merkezine hijyenik olmayan ko\u015fullarda getirilsede operasyon ba\u015far\u0131yla tamamlanm\u0131\u015ft\u0131r. Uzun s\u00fcren bir operasyonun ard\u0131ndan Kaur’un y\u00fcz\u00fc, kendi organ\u0131yla yenilenmi\u015f oldu.Asl\u0131nda bu durumu al\u0131c\u0131 ve don\u00f6r\u00fcn tek bir birey oldu\u011fu y\u00fcz nakli gibi nitelendirebiliriz.Bunun ard\u0131ndan D\u00fcnyada insandan insana ilk k\u0131smi y\u00fcz nakli 2005 y\u0131l\u0131nda, y\u00fcz\u00fc Labrador cinsi k\u00f6pe\u011fi taraf\u0131ndan par\u00e7alanan Isabelle Dinoire isimli hastaya yap\u0131ld\u0131. Fransa’da yap\u0131lan operasyonla Dinoire’n\u0131n y\u00fcz\u00fc orijinal haline d\u00f6nd\u00fcr\u00fclmeye \u00e7al\u0131\u015f\u0131l\u0131rken, hastan\u0131n a\u011f\u0131z ve burun b\u00f6lgesini de kapsayan \u00fc\u00e7gen \u015feklinde bir par\u00e7an\u0131n nakli ger\u00e7ekle\u015ftirildi.Fakat literat\u00fcrlere ilk tam y\u00fcz nakli olarak 2010 \u0130spanyol doktorlar\u0131n silah\u0131n surat\u0131nda yanl\u0131\u015fl\u0131kla ate\u015f almas\u0131 sonu\u00e7u tan\u0131nmaz hale gelen Oscar\u2019a yapt\u0131klar\u0131 nakil yer al\u0131yor.Bu y\u00fczden Frans\u0131zlar ve \u0130spanyollar literat\u00fcrdeki \u00f6nc\u00fcl\u00fck konusunda hala tart\u0131\u015fma i\u00e7indeler .Frans\u0131zlar\u0131n arg\u00fcman\u0131 k\u0131smi y\u00fcz nakli olmas\u0131na ra\u011fmen , nakil s\u0131ras\u0131nda hastaya g\u00f6zya\u015f\u0131 kanallar\u0131 ve g\u00f6zkapa\u011f\u0131 naklinin de ger\u00e7ekle\u015ftirilmi\u015f olmas\u0131 ve bu i\u015flemin \u0130spanyol doktorlar\u0131n hastas\u0131 olan Oscar\u2019a yap\u0131lmam\u0131\u015f olmas\u0131yd\u0131.Bu tart\u0131\u015fma bir s\u00fcredir devam etmekte ve bitecek gibi de g\u00f6r\u00fcnm\u00fcyor.Gelin biz \u015fimdi Y\u00dcZ NAKL\u0130\u2019nin \u00fclkemize ayak bas\u0131\u015f\u0131na bir g\u00f6z atal\u0131m.<\/strong><\/p>\n\n\n\n

\"y\u00fcz
https:\/\/foto.haberler.com\/haber\/2012\/02\/24\/yuz-nakli-yapilacak-cengiz-gul-un-enistesi-konustu-3391265_4044_o.jpg<\/figcaption><\/figure>\n\n\n\n

21 Ocak 2012’de <\/strong>T\u00fcrk<\/a> cerrah <\/strong>\u00d6mer \u00d6zkan<\/a> ve tak\u0131m\u0131 d\u00fcnyan\u0131n ilk ba\u015far\u0131l\u0131 tam y\u00fcz\nnaklini <\/strong>Antalya<\/a>‘daki <\/strong>Akdeniz \u00dcniversitesi<\/a> hastanesinde\nger\u00e7ekle\u015ftirdi. 19 ya\u015f\u0131ndaki hasta U\u011fur Acar’\u0131n, \u00e7ocukken evde \u00e7\u0131kan bir yang\u0131n\ny\u00fcz\u00fcnden, y\u00fcz\u00fc a\u011f\u0131r tahrip olmu\u015ftu. 39 ya\u015f\u0131ndaki organ ba\u011f\u0131\u015fc\u0131s\u0131 Ahmet Kaya\n2012 y\u0131l\u0131n\u0131n Ocak ay\u0131nda \u00f6lm\u00fc\u015ft\u00fc. D\u00fcnya medyas\u0131na operasyonun ba\u015far\u0131l\u0131\nge\u00e7ti\u011fi ilan edildi. Halka a\u00e7\u0131k bir etkinlikle U\u011fur Acar 21 \u015eubat 2012 g\u00fcn\u00fcnde\nbas\u0131n\u0131n \u00f6n\u00fcne \u00e7\u0131kar\u0131ld\u0131. Y\u00fcz\u00fc do\u011fal g\u00f6r\u00fcn\u00fcyordu. T\u00fcrk doktorlar onun v\u00fccudunun\nyeni dokuyu kabul etti\u011fini duyurdu. <\/strong><\/p>\n\n\n\n

24 \u015eubat 2012\ntarihinde yakla\u015f\u0131k bir ay sonra cerrah tak\u0131m\u0131 lideri <\/strong>Serdar Nas\u0131r<\/a> <\/strong>Ankara<\/a>‘daki <\/strong>Hacettepe \u00dcniversitesi<\/a>‘nde 25 ya\u015f\u0131ndaki\nhasta Cengiz G\u00fcl \u00fczerinde ikinci tam y\u00fcz naklini ger\u00e7ekle\u015ftirdi. Hastan\u0131n y\u00fcz\u00fc\niki ya\u015f\u0131ndayken televizyon t\u00fcp\u00fcn\u00fcn patlamas\u0131 sonucu a\u011f\u0131r olarak yanm\u0131\u015ft\u0131.\nAilesinin kimli\u011finin a\u00e7\u0131klanmas\u0131na izin vermedi\u011fi beyin \u00f6l\u00fcm\u00fc ger\u00e7ekle\u015fmi\u015f 40\nya\u015f\u0131ndaki ba\u011f\u0131\u015f\u00e7\u0131 N. A 17 \u015eubat tarihinde bir motosiklet kazas\u0131 s\u0131ras\u0131nda\n\u00f6lm\u00fc\u015ft\u00fc. <\/strong><\/p>\n\n\n\n

Tarihsel verilere bakt\u0131\u011f\u0131m\u0131zda\n\u00e7al\u0131\u015fmalar\u0131n \u00f6zveri\u015fli ,ciddi emek ve zeka isteyen bir di\u011fer deyi\u015fle takdire\n\u015fayan bir \u00e7al\u0131\u015fma s\u00fcrece sahip oldu\u011funu inkar edemeyiz.Ger\u00e7ek bir sanat eseri yarat\u0131lan\ny\u00fcz nakli operasyonlar\u0131 en s\u0131k Fransa\u2019da ikinci olarak da T\u00fcrkiye\u2019de\nyap\u0131lmaktad\u0131r.T\u00fcrkiye\u2019de ger\u00e7ekle\u015ftirilen nakillerin geli\u015fimi ise \u015fu \u015fekildedir.\u00d6mer\n\u00d6zkan\u2019\u0131n Akdeniz \u00dcniversitesi\u2019nde \nba\u015flatt\u0131\u011f\u0131 bu muazzam y\u00fcz nakli maceras\u0131, ikinci olarak   Hacettepe \u00dcniversitesi\u2019nde Cengiz G\u00fcl\u2019e,\n\u00fc\u00e7\u00fcnc\u00fc olarak Gazi \u00dcniversitesi\u2019nde Hatice Nergis\u2019e, d\u00f6rd\u00fcnc\u00fc olarak  Akdeniz \u00dcniversitesi\u2019nde Turan \u00c7olak\u2019a,\nbe\u015finci olarak  Akdeniz \u00dcniversitesi\u2019nde Recep\nSert\u2019e, alt\u0131nc\u0131 olarak  Salih \u00dcsl\u00fcn\u2019e ve\nyedinci olarak Akdeniz \u00dcniversitesi\u2019nde Recep Kaya\u2019ya ger\u00e7ekle\u015ftirildi. Bug\u00fcne\nkadar yap\u0131lan y\u00fcz nakil ameliyat\u0131ndan iki ki\u015fi, ameliyat sonras\u0131 kullan\u0131lan\nila\u00e7lar ve doku uyu\u015fmazl\u0131\u011f\u0131 sebebiyle hayat\u0131n\u0131 kaybetti.<\/h5>\n\n\n\n

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Yaz\u0131 dizimizin bir\nsonraki b\u00f6l\u00fcm\u00fc \u201cY\u00dcZ NAKL\u0130NDE DON\u00d6R VE AKICI ARASINDAK\u0130 DOKU UYUMU NASIL\nGER\u00c7EKLE\u015e\u0130R?\u201c  yaz\u0131s\u0131yla devam edecek\u2026.<\/strong><\/p>\n\n\n\n

Yararland\u0131\u011f\u0131m\nkaynaklar;<\/strong><\/p>\n\n\n\n

http:\/\/www.journalagent.com\/z4\/vi.asp?pdir=tybdd&plng=tur&un=TYBDD-08760&look4<\/a> (\u201cY\u00dcZ NAKL\u0130\u201d HABERLER\u0130N\u0130N SUNUMU<\/a>)<\/h6>\n\n\n\n

http:\/\/www.academia.edu\/download\/45512377\/396-410_Asuman_Kaya___E._Yuksel_vd_SON_HALI.docx<\/a><\/p>\n\n\n\n

https:\/\/tr.wikipedia.org\/wiki\/Y%C3%BCz_nakli<\/a><\/p>\n\n\n\n

https:\/\/www.hurriyet.com.tr\/kelebek\/saglik\/turkiyenin-yuz-nakli-seruveni-boyle-basladi-26634522<\/a><\/p>\n\n\n\n

http:\/\/www.plastikcerrahi.org.tr\/<\/a><\/strong>https:\/\/pdfs.semanticscholar.org\/bf78\/66e5f674cfb6dc490d28622e39f5ef2a82a3.pdf<\/a>(T\u00fcrkiye’de <\/strong>organ ve doku <\/strong>nakli uygulamalar\u0131:\nSonu\u00e7lar\u0131 ve strateji \u00f6nerileri<\/strong><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Organ ve doku nakli, i\u015flevini kaybetmi\u015f organ\u0131n yerine  canl\u0131 bir don\u00f6rden (verici) veyahut beyin \u00f6l\u00fcm\u00fc ger\u00e7ekle\u015fmi\u015f ki\u015fiden al\u0131nan sa\u011flam organ\u0131n<\/p>\n","protected":false},"author":146,"featured_media":5196,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[1],"tags":[182,647],"acf":[],"views":1324,"_links":{"self":[{"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/posts\/5194"}],"collection":[{"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/users\/146"}],"replies":[{"embeddable":true,"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/comments?post=5194"}],"version-history":[{"count":4,"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/posts\/5194\/revisions"}],"predecessor-version":[{"id":5201,"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/posts\/5194\/revisions\/5201"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/media\/5196"}],"wp:attachment":[{"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/media?parent=5194"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/categories?post=5194"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/tags?post=5194"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}