{"id":6520,"date":"2020-07-25T09:56:07","date_gmt":"2020-07-25T06:56:07","guid":{"rendered":"http:\/\/blog.ulubat.org\/?p=6520"},"modified":"2020-07-25T09:56:09","modified_gmt":"2020-07-25T06:56:09","slug":"karl-landsteiner-abo-kan-grup-sistemini-gelistirmesiyle-insanlik-tarihine-buyuk-katki-saglayan-bilim-insani","status":"publish","type":"post","link":"https:\/\/blog.ulubat.org\/index.php\/genel\/karl-landsteiner-abo-kan-grup-sistemini-gelistirmesiyle-insanlik-tarihine-buyuk-katki-saglayan-bilim-insani\/","title":{"rendered":"KARL LANDSTEINER- ABO KAN GRUP S\u0130STEM\u0130N\u0130 GEL\u0130\u015eT\u0130RMES\u0130YLE \u0130NSANLIK TAR\u0130H\u0130NE B\u00dcY\u00dcK KATKI SA\u011eLAYAN B\u0130L\u0130M \u0130NSANI"},"content":{"rendered":"\n
\"\"<\/figure>\n\n\n\n

Karl Landsteiner, 14 Haziran 1868 tarihinde Viyana\u2019da d\u00fcnyaya geldi. Babas\u0131 Leopold Landsteiner, Karl 6 ya\u015f\u0131ndayken vefat etti. Karl, annesi Fanny Hess taraf\u0131ndan yeti\u015ftirildi. Erken ya\u015fta okul hayat\u0131na ba\u015flayan Karl, her zaman parlak bir \u00f6\u011frenci oldu.<\/p>\n\n\n\n

1885 y\u0131l\u0131nda Viyana \u00dcniversitesinde t\u0131p e\u011fitimine ba\u015flad\u0131. Bilim \u00e7al\u0131\u015fmalar\u0131na \u00f6\u011frencilik d\u00f6neminde ba\u015flad\u0131 ve kan bile\u015fenlerine diyetlerin etkisi \u00fczerine bir makale yazd\u0131.1891 y\u0131l\u0131nda \u00fcniversiteden mezun oldu ve 5 y\u0131l M\u00fcnih\u2019te \u00e7e\u015fitli laboratuvarlarda \u00e7al\u0131\u015ft\u0131. 1896 y\u0131l\u0131nda Viyana\u2019ya geri d\u00f6nd\u00fc ve Hijyen Enstit\u00fcs\u00fc\u2019nde Doktor Max Von Gruber\u2019in asistan\u0131 oldu.<\/p>\n\n\n\n

1898 y\u0131l\u0131nda Viyana Patoloji Enstit\u00fcs\u00fc\u2019nde Patolojik Anatomi B\u00f6l\u00fcm\u00fc\u2019nde ara\u015ft\u0131rmac\u0131 olarak \u00e7al\u0131\u015fmaya ba\u015flayan Karl, daha sonra morbid fizyolojisi ve anatomisi \u00fczerine \u00e7al\u0131\u015fmalar yapt\u0131. <\/p>\n\n\n\n

Viyana Patoloji Enstit\u00fcs\u00fc\u2019nde ara\u015ft\u0131rmac\u0131 olarak \u00e7al\u0131\u015f\u0131rken insanlar\u0131n kan yap\u0131s\u0131ndaki farkl\u0131l\u0131klar\u0131 bularak, kan nakillerindeki tehlikeyi ortaya \u00e7\u0131karm\u0131\u015ft\u0131r. 1901 y\u0131l\u0131nda, A,B,O olmak \u00fczere \u00fc\u00e7 kan grubu oldu\u011funu kan\u0131tlad\u0131. Bu kan gruplar\u0131, alyuvarlardaki h\u00fccre zar\u0131n\u0131n d\u0131\u015f katman\u0131na ba\u011flanan antijenlere g\u00f6re belirleniyordu. Bir y\u0131l sonra da A ve B antijenlerinin ikisini birden ta\u015f\u0131yan AB kan grubu bulundu. Daha sonra Karl Landsteiner, kan gruplar\u0131 ve ba\u011f\u0131\u015f\u0131kl\u0131k alan\u0131ndaki \u00e7al\u0131\u015fmalar\u0131yla tan\u0131nm\u0131\u015ft\u0131r. Kan nakilleri \u00e7o\u011fu kez \u00f6l\u00fcmle sonu\u00e7land\u0131\u011f\u0131 i\u00e7in 19.y\u00fczy\u0131l\u0131n sonlar\u0131na do\u011fru bir\u00e7ok \u00fclkede yasaklanm\u0131\u015ft\u0131. Bu \u00f6l\u00fcmlerin nedenini ara\u015ft\u0131rmaya ba\u015flayan Landsteiner, \u00e7al\u0131\u015fmalar\u0131n\u0131 kan serumu ve alyuvarlar aras\u0131ndaki antijen antikor tepkimelerine y\u00f6neltti. <\/p>\n\n\n\n

1908 y\u0131l\u0131nda Viyana\u2019da Wilhelm Kraliyet Hastanesinde g\u00f6reve ba\u015flad\u0131. Landsteiner, yine o d\u00f6nemin \u00f6nemli sorunlar\u0131ndan biri olan \u00e7ocuk felci hastal\u0131\u011f\u0131 ile ara\u015ft\u0131rmalar yap\u0131yordu.         Bu hastal\u0131ktan \u00f6len bir \u00e7ocu\u011fun beyin omurilik s\u0131v\u0131s\u0131n\u0131 maymunlara enjekte ederek hastal\u0131k yap\u0131c\u0131 etkenin vir\u00fcs oldu\u011funu ilk kez Landsteiner a\u00e7\u0131klad\u0131. B\u00f6ylece Poliomyelitin imm\u00fcnolojisi ile ilgili bug\u00fcnk\u00fc bilgilerimizin temellerini att\u0131. 1911 y\u0131l\u0131nda Viyana \u00dcniversitesi\u2019nde Patolojik Anatomi Profes\u00f6r\u00fc olan Landsteiner, imm\u00fcnoloji ve morbid anatomi alan\u0131nda \u00e7al\u0131\u015fmalar\u0131na devam etti.  Anatomi ve imm\u00fcnoloji \u00fczerine makaleler yay\u0131nlad\u0131. Haptenleri ke\u015ffederek Wasserman reaksiyonlar\u0131na yeni bilgiler ekledi.<\/p>\n\n\n\n

1916 y\u0131l\u0131nda Helen Wlasto ile evlenen Karl Landsteiner, 1919 y\u0131l\u0131nda Avusturya\u2019dan ayr\u0131ld\u0131 ve Hollanda\u2019n\u0131n La Haye kentinde bir hastanede ara\u015ft\u0131rmalar\u0131na h\u0131z kesmeden devam etti. Burada, farkl\u0131 hayvan t\u00fcrlerindeki hemoglobinlerin serolojik \u00f6zg\u00fcll\u00fc\u011f\u00fc, anaflaksiyi uyaran protein ile konjugatlar\u0131 ve yeni buldu\u011fu haptenler ile ilgili yakla\u015f\u0131k 12 makale yay\u0131nlad\u0131. Karl Landsteiner, 1922 y\u0131l\u0131nda Amerika Birle\u015fik Devletleri(ABD) vatanda\u015fl\u0131\u011f\u0131na ge\u00e7ti ve Newyork\u2019a yerle\u015fti. Newyork\u2019taki Rockefeller T\u0131bbi Ara\u015ft\u0131rma Enstit\u00fcs\u00fc\u2019nde patoloji dersleri vermeye ba\u015flad\u0131. 1927 y\u0131l\u0131nda M ve N kan gruplar\u0131n\u0131 bulan Landsteiner, 1936 y\u0131l\u0131nda Serolojik Tepkimelerin \u00d6zg\u00fcrl\u00fc\u011f\u00fc eserini haz\u0131rlad\u0131. Bu eser, ba\u011f\u0131\u015f\u0131kl\u0131k kimyas\u0131n\u0131n kurulmas\u0131na b\u00fcy\u00fck katk\u0131 sa\u011flam\u0131\u015ft\u0131r. 1940 y\u0131l\u0131nda ilk kez bulundu\u011fu maymun t\u00fcr\u00fcn\u00fcn ad\u0131n\u0131 ta\u015f\u0131yan Rhesus(Rh) fakt\u00f6r\u00fcn\u00fc buldu. Rh fakt\u00f6r\u00fc ;  anne ve bebek aras\u0131nda kan uyu\u015fmazl\u0131\u011f\u0131na sebep oluyordu. Karl Landsteiner, \u00e7al\u0131\u015fmalar\u0131yla adli t\u0131p alal\u0131nda b\u00fcy\u00fck faydalar sa\u011flad\u0131; babal\u0131k ve cinayet davalar\u0131nda kan gruplar\u0131n\u0131n kan\u0131t olarak kullan\u0131lmas\u0131n\u0131 sa\u011flad\u0131. Kan gruplar\u0131n\u0131n genler arac\u0131l\u0131\u011f\u0131 ile ku\u015faktan ku\u015fa\u011fa aktar\u0131ld\u0131\u011f\u0131n\u0131n ispatlanmas\u0131, kal\u0131t\u0131m ve antropoloji ara\u015ft\u0131rmalar\u0131nda \u00f6nemli bir y\u00f6ntem oldu. <\/p>\n\n\n\n

NOBEL \u00d6D\u00dcL\u00dc<\/p>\n\n\n\n

Karl Landsteiner, ba\u015fl\u0131ca kan gruplar\u0131n\u0131 bulmas\u0131 ve kan naklinin t\u0131pta pratik bir uygulama haline gelmesini sa\u011flayan ABO kan gruplar\u0131 sistemini geli\u015ftirmesiyle 1930 y\u0131l\u0131nda Nobel Fizyoloji veya T\u0131p \u00d6d\u00fcl\u00fc\u2019n\u00fc ald\u0131.<\/p>\n\n\n\n

\u00d6L\u00dcM\u00dc<\/p>\n\n\n\n

24 Haziran 1943 tarihinde laboratuvarda kalp krizi ge\u00e7irdi ve 26 Haziran 1943 tarihinde vefat etti.  Google taraf\u0131ndan Karl Landsteiner i\u00e7in \u201cDoodle\u201d haz\u0131rland\u0131 ve bu sayede herkes onun kim oldu\u011funu merak etti. Yapm\u0131\u015f oldu\u011fu ke\u015fifler insanl\u0131k i\u00e7in b\u00fcy\u00fck \u00f6nem ta\u015f\u0131maktad\u0131r.<\/p>\n\n\n\n

KAYNAK\u00c7A<\/p>\n\n\n\n

 1)Karl\nLandsteiner<\/p>\n\n\n\n

    Son\ng\u00fcncelleme tarihi: 24\nOcak 2019<\/p>\n\n\n\n

https:\/\/www.labmedya.com\/karl-landsteiner<\/a><\/p>\n\n\n\n

2) Karl\nLandsteiner Kimdir? Google Landsteiner\u2019in do\u011fum g\u00fcn\u00fcn\u00fc unutmad\u0131<\/p>\n\n\n\n

    Son\ng\u00fcncelleme tarihi:16 Haziran 2016<\/p>\n\n\n\n

https:\/\/www.mynet.com\/karl-landsteiner-kimdir-google-landsteinerin-dogum-gununu-unutmadi-110102496127<\/a><\/p>\n\n\n\n

 3) Karl\nLandsteiner Kimdir? Hayat\u0131m\u0131z\u0131 De\u011fi\u015ftiren Bulu\u015fu Nedir? Eserleri Nelerdir?<\/p>\n\n\n\n

     Son\ng\u00fcncelleme tarihi: 12 \u015eubat 2019<\/p>\n\n\n\n

https:\/\/www.bolgegundem.com\/karl-landsteiner-kimdir-hayatimizi-degistiren-bulusu-nedir-eserleri-nelerdir-730905h.htm<\/a><\/p>\n\n\n\n

  G\u00d6RSEL\nKAYNAK<\/p>\n\n\n\n

 1) Karl Landsteiner<\/p>\n\n\n\n

    Son\ng\u00fcncelleme tarihi: 24 Ocak 2019<\/p>\n\n\n\n

https:\/\/www.labmedya.com\/karl-landsteiner<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Karl Landsteiner, 14 Haziran 1868 tarihinde Viyana\u2019da d\u00fcnyaya geldi. Babas\u0131 Leopold Landsteiner, Karl 6 ya\u015f\u0131ndayken vefat etti. Karl, annesi Fanny<\/p>\n","protected":false},"author":269,"featured_media":6522,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[1],"tags":[],"acf":[],"views":580,"_links":{"self":[{"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/posts\/6520"}],"collection":[{"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/users\/269"}],"replies":[{"embeddable":true,"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/comments?post=6520"}],"version-history":[{"count":2,"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/posts\/6520\/revisions"}],"predecessor-version":[{"id":6524,"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/posts\/6520\/revisions\/6524"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/media\/6522"}],"wp:attachment":[{"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/media?parent=6520"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/categories?post=6520"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/tags?post=6520"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}