{"id":7026,"date":"2020-09-26T14:49:45","date_gmt":"2020-09-26T11:49:45","guid":{"rendered":"http:\/\/blog.ulubat.org\/?p=7026"},"modified":"2020-09-26T15:11:19","modified_gmt":"2020-09-26T12:11:19","slug":"hiv-ile-gecen-bir-omur-francoise-barre-sinoussi","status":"publish","type":"post","link":"https:\/\/blog.ulubat.org\/index.php\/genel\/hiv-ile-gecen-bir-omur-francoise-barre-sinoussi\/","title":{"rendered":"HIV ile Ge\u00e7en Bir \u00d6m\u00fcr: Fran\u00e7oise Barr\u00e9-Sinoussi"},"content":{"rendered":"\n

Virolog Fran\u00e7oise Barr\u00e9-Sinoussi, insan ba\u011f\u0131\u015f\u0131kl\u0131k\nyetmezli\u011fi vir\u00fcs\u00fc (HIV) hakk\u0131ndaki \u00e7al\u0131\u015fmalar\u0131yla tan\u0131n\u0131r. Pasteur\nEnstit\u00fcs\u00fc\u2019nde Emeritus Profes\u00f6r ve Retroviral Enfeksiyonlar Kontrol Birimi\u2019nin\ndirekt\u00f6r\u00fcd\u00fcr.  <\/strong><\/p>\n\n\n\n

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https:\/\/www.flickr.com\/photos\/acmedsci\/8243168345\/<\/a> <\/figcaption><\/figure><\/div>\n\n\n\n

Ki\u015fisel Ya\u015fam\u0131 ve\nKariyerinin \u0130lk Zamanlar\u0131<\/strong><\/p>\n\n\n\n

1947\u2019de Paris\u2019te do\u011fdu. \u00c7ocuklu\u011fu \u00e7o\u011fu zaman k\u0131rsalda\nge\u00e7ti. Bu y\u00fczden do\u011fay\u0131 g\u00f6zlemlemeyi hep sevdi ve bu sevgi kariyer se\u00e7imini de\netkiledi.<\/p>\n\n\n\n

Liseyi bitirdikten sonra do\u011fa bilimleri alan\u0131nda\n\u00e7al\u0131\u015fmaya karar vererek Paris \u00dcniversitesi\u2019nde Fen Fak\u00fcltesi\u2019ne kaydoldu.  Okulunun son y\u0131l\u0131nda retrovir\u00fcsler ile kanser\nili\u015fkisini ara\u015ft\u0131ran bir ara\u015ft\u0131rma grubunda g\u00f6n\u00fcll\u00fc olarak \u00e7al\u0131\u015fma imk\u00e2n\u0131\nbuldu.  Burada ge\u00e7irdi\u011fi zamanlar bilim\ntutkusunu daha da art\u0131rd\u0131.\n<\/strong><\/p>\n\n\n\n

Pasteur Enstit\u00fcs\u00fc\u2019nden doktora derecesi ald\u0131ktan sonra, ABD\u2019de Ulusal Kanser Enstit\u00fcs\u00fc\u2019nde doktora sonras\u0131 \u00e7al\u0131\u015fmas\u0131n\u0131 Murin l\u00f6semi vir\u00fcs\u00fc<\/strong> hakk\u0131nda yapt\u0131.<\/p>\n\n\n\n

ABD\u2019de tan\u0131\u015ft\u0131\u011f\u0131 Jean-Claude Barre ile 1978 y\u0131l\u0131nda evlendi.<\/p>\n\n\n\n

\u201cBilim ger\u00e7ekten bir tutkudur. Bilime bu \u015fekilde bakmazlarsa, bunu sadece bir meslek olarak g\u00f6r\u00fcrler. Kendiniz, \u00f6zge\u00e7mi\u015finiz i\u00e7in, yay\u0131n yapmak, tan\u0131nmak i\u00e7in de\u011fil toplum i\u00e7in bilim insan\u0131 olmaya ger\u00e7ekten motive olmu\u015fsan\u0131z yapabilece\u011finiz en g\u00fczel i\u015f budur.\u201d<\/p><\/blockquote>\n\n\n\n

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https:\/\/www.flickr.com\/photos\/fleshmanpix\/7759533720\/in\/photostream\/<\/a> <\/figcaption><\/figure><\/div>\n\n\n\n

En b\u00fcy\u00fck \u00e7al\u0131\u015fmas\u0131:\nHIV ke\u015ffi<\/strong><\/p>\n\n\n\n

Amerika\u2019dayken, Fransa Ulusal Sa\u011fl\u0131k ve T\u0131bbi Ara\u015ft\u0131rma Enstit\u00fcs\u00fc taraf\u0131ndan bir laboratuvarda \u00e7al\u0131\u015fma ile \u00f6d\u00fcllendirildi. Laboratuvar Profes\u00f6r Luc Montagnier\u2019in birimindeydi ve retrovir\u00fcsler hakk\u0131nda \u00e7al\u0131\u015fmalar yap\u0131l\u0131yordu.<\/p>\n\n\n\n

1980\u2019lerde d\u00fcnyada AIDS epidemisi ba\u015flad\u0131. Bir\u00e7ok\nbilim insan\u0131 gibi Luc Montagnier de bu epidemi \u00fczerine \u00e7al\u0131\u015fmaya ba\u015flad\u0131.\n\u201cHastal\u0131\u011f\u0131n sebebi bir retrovir\u00fcs olabilir.\u201d d\u00fc\u015f\u00fcncesiyle ara\u015ft\u0131rma projesine\nba\u015flad\u0131 ve Barr\u00e9-Sinoussi\u2019ye bu projede \u00e7al\u0131\u015fmay\u0131 teklif etti.  <\/p>\n\n\n\n

Barr\u00e9-Sinoussi ve Montagnier, hastal\u0131\u011f\u0131n erken evresindeki, lenfadenopatili hastalardan lenf d\u00fc\u011f\u00fcm\u00fcnden \u00f6rnek ald\u0131 ve vir\u00fcs\u00fc izole etti ve 1983\u2019te etkeni ke\u015ffettiler. Bu ke\u015fiflerinin ad\u0131 HIV<\/strong> ya da o zaman verilen ad\u0131yla LAV<\/strong>\u2019d\u0131.<\/p>\n\n\n\n

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HIV viral ya\u015fam d\u00f6ng\u00fcs\u00fc, ill\u00fcstrasyon (\u00fcstte k\u0131rm\u0131z\u0131, mor k\u0131s\u0131m vir\u00fcs\u00fc; alttaki mavi, ye\u015fil k\u0131s\u0131m h\u00fccreyi g\u00f6steriyor.)


https:\/\/wellcomecollection.org\/works\/enep9d4h<\/a> <\/figcaption><\/figure><\/div>\n\n\n\n

HIV\/A\u0130DS Alan\u0131nda\n\u00c7al\u0131\u015fmalar\u0131<\/strong><\/p>\n\n\n\n

Pasteur Enstit\u00fcs\u00fc\u2019nde kendi sorumlulu\u011fundaki laboratuvar\u0131nda HIV \/ AIDS patogenezi, HIV a\u015f\u0131s\u0131<\/strong> gibi konularda ara\u015ft\u0131rmalar yapt\u0131. 1992\u2019de Retrovir\u00fcs Biyolojisi Birimi\u2019nin ba\u015f\u0131na atand\u0131. 2005\u2019te birim yeniden d\u00f6n\u00fc\u015ft\u00fcr\u00fclerek Retroviral Enfeksiyonlar Kontrol Birimi<\/strong> ad\u0131n\u0131 ald\u0131.<\/p>\n\n\n\n

\u0130mk\u00e2nlar\u0131 k\u0131s\u0131tl\u0131 olan \u00fclkelerden gen\u00e7 bilim insanlar\u0131\nve Paris’teki ara\u015ft\u0131rmac\u0131lar aras\u0131nda HIV konusunda s\u00fcrekli bir i\u015f birli\u011fi\nolu\u015fturdu. <\/p>\n\n\n\n

2009’da, Papa 16. Benedict\u2019i prezervatiflerin A\u0130DS\u2019ten\nkorunmaya kar\u015f\u0131 etkisiz oldu\u011fu \u015feklindeki a\u00e7\u0131klamalar\u0131ndan dolay\u0131 a\u00e7\u0131k bir\nmektup yazarak onu protesto etti.<\/p>\n\n\n\n

Temmuz 2012’de Barr\u00e9-Sinoussi, Uluslararas\u0131 AIDS Toplulu\u011fu<\/strong>\u2019nun ba\u015fkan\u0131 oldu ve iki y\u0131l boyunca bu g\u00f6revini s\u00fcrd\u00fcrd\u00fc. Fransa’daki Ulusal AIDS Ara\u015ft\u0131rma Ajans\u0131 gibi di\u011fer AIDS organizasyonlar\u0131na aktif olarak katk\u0131da bulundu.<\/p>\n\n\n\n

\u201cAIDS\u2019ten etkilenen kad\u0131nlarla ya da uyu\u015fturucu kullan\u0131c\u0131lar\u0131yla konu\u015ftu\u011fumda g\u00f6rd\u00fcm ki bilimden \u00e7ok \u015fey bekliyorlar. Bize inan\u0131yorlar, bu nedenle beklentilerine cevap vermek i\u00e7in elimizden gelenin en iyisini yapmaya \u00e7al\u0131\u015fmak bizim g\u00f6revimizdir.”<\/p><\/blockquote>\n\n\n\n

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https:\/\/commons.wikimedia.org\/wiki\/File:Fran\u00e7oise_Barr\u00e9-Sinoussi-press_conference_Dec_06th,_2008-1.jpg <\/figcaption><\/figure><\/div>\n\n\n\n

Nobel \u00d6d\u00fcl\u00fc ve Di\u011fer\nBa\u015far\u0131lar<\/strong><\/p>\n\n\n\n

Luc Montagnier ile HIV ke\u015ffindeki \u00e7al\u0131\u015fmalar\u0131ndan dolay\u0131 birlikte 2008 Nobel Fizyoloji veya T\u0131p \u00d6d\u00fcl\u00fc<\/strong>‘ne lay\u0131k g\u00f6r\u00fcld\u00fc. Kariyeri boyunca, Nobel T\u0131p \u00d6d\u00fcl\u00fc haricinde bir\u00e7ok ulusal veya uluslararas\u0131 \u00f6d\u00fcl ald\u0131. Bir\u00e7ok \u00fcniversite taraf\u0131ndan fahri doktora ile \u00f6d\u00fcllendirildi. Ayr\u0131ca Frans\u0131z Bilim Akademisi<\/strong> \u00fcyeli\u011fine se\u00e7ildi. <\/p>\n\n\n\n

Bunlar\u0131n d\u0131\u015f\u0131nda 120\u2019den fazla makale yazd\u0131, 200\u2019den\nfazla kongrede bildiri yay\u0131nlad\u0131.<\/p>\n\n\n\n

G\u00fcn\u00fcm\u00fczde<\/strong><\/p>\n\n\n\n

68 ya\u015f\u0131nda, bir se\u00e7im de\u011fil bir gereklilik oldu\u011funu belirterek, emekli oldu fakat HIV \/ SIV enfeksiyonlar\u0131na kar\u015f\u0131 korunma ve AIDS’in kontrol\u00fc \u00fczerine \u00e7al\u0131\u015fmalar\u0131na devam ediyor.<\/p>\n\n\n\n

Notlar:<\/strong><\/p>\n\n\n\n

  • Emeritus Profes\u00f6r: <\/strong>Emekli\nolmu\u015f ancak akademik \u00e7al\u0131\u015fmalar\u0131na devam eden ki\u015filere verilen unvan<\/li>
  • Murin L\u00f6semi vir\u00fcs\u00fc:<\/strong>\nS\u0131\u00e7an ve farelerde kansere neden olan bir retrovir\u00fcs.<\/li>
  • Lenfadenopati<\/strong>:\nLenf bezinde b\u00fcy\u00fcme.<\/li>
  • LAV:<\/strong> Lenfadenopatiyle\nili\u015fkili vir\u00fcs, HIV\u2019e ilk verilen ad.<\/li>
  • SIV:<\/strong>\nMaymun ba\u011f\u0131\u015f\u0131kl\u0131k yetmezli\u011fi vir\u00fcs\u00fc olarak bilinen HIV benzeri vir\u00fcs.<\/li><\/ul>\n\n\n\n

    <\/p>\n\n\n\n

    V\u0130DEO: HIV vir\u00fcs\u00fcn\u00fc yok etmeye ne kadar yak\u0131n\u0131z?<\/p>\n\n\n\n

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