{"id":7489,"date":"2020-10-26T12:02:39","date_gmt":"2020-10-26T09:02:39","guid":{"rendered":"http:\/\/blog.ulubat.org\/?p=7489"},"modified":"2020-10-26T12:03:30","modified_gmt":"2020-10-26T09:03:30","slug":"gerty-theresa-cori","status":"publish","type":"post","link":"https:\/\/blog.ulubat.org\/index.php\/genel\/gerty-theresa-cori\/","title":{"rendered":"Gerty Theresa Cori"},"content":{"rendered":"\n
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https:\/\/commons.wikimedia.org\/wiki\/File:Gerty_Theresa_Cori.jpg <\/figcaption><\/figure>\n\n\n\n

\u00dcnl\u00fc biyokimyac\u0131 Gerty Theresa Cori, ABD\u2019de Nobel \u00d6d\u00fcl\u00fc alan ilk kad\u0131nd\u0131r. Yapt\u0131\u011f\u0131 ke\u015fiflerle karbonhidrat metabolizmas\u0131yla ilgili bir\u00e7ok bilinmezi a\u00e7\u0131\u011fa kavu\u015fturmu\u015ftur.<\/p>\n\n\n\n

1896 y\u0131l\u0131nda Prag, \u00c7ekoslovakya’da d\u00fcnyaya geldi. Lise \u00f6ncesi e\u011fitimini evde tamamlad\u0131. Pediatri profes\u00f6r\u00fc olan amcas\u0131, onu t\u0131p okumaya te\u015fvik etti. T\u0131p fak\u00fcltesinden 1920 y\u0131l\u0131nda mezun oldu. Mezun olduktan k\u0131sa bir s\u00fcre sonra fak\u00fclte y\u0131llar\u0131nda tan\u0131\u015ft\u0131\u011f\u0131 Carl Ferdinand Cori ile evlendi.<\/p>\n\n\n\n

Bilimsel Ya\u015fam\u0131<\/strong><\/p>\n\n\n\n

Carolinen \u00c7ocuk Hastanesi\u2019nde iki y\u0131l \u00e7al\u0131\u015ft\u0131. Daha sonra \u00e7ift Avrupa\u2019daki gergin siyasi iklimden dolay\u0131 1922\u2019de ABD\u2019deki Buffalo \u015fehrine ta\u015f\u0131nd\u0131.  Yard\u0131mc\u0131 patolog olarak i\u015fe ba\u015flayan Gerty Cori, daha sonra e\u015fiyle beraber biyokimya<\/strong> alan\u0131nda uzmanla\u015ft\u0131. E\u015fi Carl ile okul y\u0131llar\u0131ndan beri preklinik alanlara ilgi duyuyorlard\u0131 ve bu ilgileri onlar\u0131 beraber \u00e7al\u0131\u015fmaya y\u00f6nlendirdi.<\/p>\n\n\n\n

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Gerty ve Carl Cori
https:\/\/commons.wikimedia.org\/wiki\/File:Gerty_Theresa_Radnitz_Cori_(1896-1957)_and_Carl_Ferdinand_Cori.jpg<\/figcaption><\/figure>\n\n\n\n

E\u015fiyle beraber \u015fekerin hayvanlardaki ak\u0131beti ve ins\u00fclin ve epinefrinin glikoz \u00fczerindeki etkileri \u00fczerine \u00e7al\u0131\u015ft\u0131. \u201cCori esteri\u201d <\/strong>olarak da glikoz-1-fosfat\u0131<\/strong> izole etti. Glikojen ve ni\u015fastan\u0131n in vitro<\/em> enzimatik sentezini bu ke\u015fif sayesinde sa\u011fland\u0131. Glikozun kas glikojenine d\u00f6n\u00fc\u015fmesinde laktik asidin rol\u00fcn\u00fc g\u00f6sterdi ki bu \u201cCori d\u00f6ng\u00fcs\u00fc\u201d <\/strong>olarak bilinir. Bu iki ke\u015fif ile bir\u00e7ok \u00f6d\u00fcle lay\u0131k g\u00f6r\u00fcld\u00fcler. Ayr\u0131ca hormonlar\u0131n etki mekanizmas\u0131 ve hipofiz \u00fczerinde \u00e7e\u015fitli \u00e7al\u0131\u015fmalar da y\u00fcr\u00fctt\u00fc.<\/p>\n\n\n\n

\u00c7al\u0131\u015fmalara\nayn\u0131 eme\u011fi harcam\u0131\u015f olsalar da Gerty Cori\u2019ye ara\u015ft\u0131rma asistanl\u0131\u011f\u0131 i\u00e7in teklif\ngelirken e\u015fine profes\u00f6rl\u00fck teklifleri geliyordu. On alt\u0131 y\u0131l boyunca asistan\nolarak \u00e7al\u0131\u015ft\u0131.<\/p>\n\n\n\n

1947\u2019de biyokimya profes\u00f6rl\u00fc\u011f\u00fcne terfi etti ve ayn\u0131 y\u0131l e\u015fiyle beraber Nobel T\u0131p veya Fizyoloji \u00d6d\u00fcl\u00fc<\/strong>\u2019ne lay\u0131k g\u00f6r\u00fcld\u00fc. Bunun d\u0131\u015f\u0131nda \u00e7e\u015fitli \u00f6d\u00fcller ve Boston, Cambridge, Yale \u00fcniversitelerinden fahri doktora<\/strong> ald\u0131.<\/p>\n\n\n\n

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Gerty Cori ve e\u015fi Carl Cori Nobel \u00d6d\u00fcl\u00fc t\u00f6reninde
https:\/\/commons.wikimedia.org\/wiki\/File:Gerty_and_Carl_Cori_at_the_Nobel_Prize.jpg<\/figcaption><\/figure>\n\n\n\n

Gerty ve\nCarl Cori ile birbirlerine verdikleri destek ve ortak \u00e7al\u0131\u015fmalar\u0131yla bilim\nd\u00fcnyas\u0131nda g\u00fczel bir \u00f6rnek oldu. Gerty Cori, 26 Ekim 1957’de hayat\u0131n\u0131 kaybetti.<\/p>\n\n\n\n

Kaynaklar:<\/strong><\/p>\n\n\n\n

  1. Gerty Cori \u2013 Biographical Al\u0131nd\u0131\u011f\u0131\nTarih: 11 Ekim 2020 Al\u0131nd\u0131\u011f\u0131 Yer: https:\/\/www.nobelprize.org\/prizes\/medicine\/1947\/cori-gt\/biographical\/<\/a><\/li>
  2. Dr. Gerty Theresa Radnitz Cori\nAl\u0131nd\u0131\u011f\u0131 Tarih: 11 Ekim 2020 Al\u0131nd\u0131\u011f\u0131 Yer: https:\/\/cfmedicine.nlm.nih.gov\/physicians\/biography_69.html<\/a>\n<\/li><\/ol>\n","protected":false},"excerpt":{"rendered":"

    \u00dcnl\u00fc biyokimyac\u0131 Gerty Theresa Cori, ABD\u2019de Nobel \u00d6d\u00fcl\u00fc alan ilk kad\u0131nd\u0131r. Yapt\u0131\u011f\u0131 ke\u015fiflerle karbonhidrat metabolizmas\u0131yla ilgili bir\u00e7ok bilinmezi a\u00e7\u0131\u011fa kavu\u015fturmu\u015ftur.<\/p>\n","protected":false},"author":265,"featured_media":8067,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[1],"tags":[946,1271,1269,453,947],"acf":[],"views":1272,"_links":{"self":[{"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/posts\/7489"}],"collection":[{"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/users\/265"}],"replies":[{"embeddable":true,"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/comments?post=7489"}],"version-history":[{"count":13,"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/posts\/7489\/revisions"}],"predecessor-version":[{"id":8079,"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/posts\/7489\/revisions\/8079"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/media\/8067"}],"wp:attachment":[{"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/media?parent=7489"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/categories?post=7489"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/tags?post=7489"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}