![\"\"](\"https:\/\/blog.ulubat.org\/wp-content\/uploads\/2020\/11\/man-2125123_640-1024x1024.png\")
<\/figure><\/div>\n\n\n\nABD ve \u0130talya\u2019da g\u00f6r\u00fclen baz\u0131 davalarda su\u00e7lular, genotiplerindeki bu mutasyonlar\u0131 kan\u0131t olarak sunarak cezan\u0131n hafifletilmesi istedi. 5 vakada ise bu farkl\u0131l\u0131klar nedeniyle su\u00e7a yatk\u0131n oldu\u011fu sonucu \u00e7\u0131kar\u0131l\u0131p ceza indirimine gidildi. Bu durum say\u0131l\u0131 olsa da geneti\u011fin davran\u0131\u015flar\u0131m\u0131z\u0131 ne kadar etkiledi\u011fini g\u00f6z ard\u0131 etmememiz gerekti\u011fini g\u00f6sterdi. <\/p>\n\n\n\n
Bu genetik farkl\u0131l\u0131\u011f\u0131n MAO-A geni \u00fczerindeki mutasyon sonucu olu\u015fmaktad\u0131r. Bu genin g\u00f6revlerine ve mutasyon etkilerine bakarak irdeleyelim. <\/p>\n\n\n\n
Nedir bu MAO-A?<\/h2>\n\n\n\n
MAO-A geni X kromozomu \u00fczerinde bulunan bir gendir. Erkeklerde daha s\u0131k kar\u015f\u0131la\u015fmakla beraber kad\u0131nlarda mutasyon ger\u00e7ekle\u015fti\u011finde daha az tutarl\u0131 bulgularla kar\u015f\u0131la\u015f\u0131lm\u0131\u015ft\u0131r. <\/p>\n\n\n\n
Monoamin Oksidaz-A normal beyin fonksiyonlar\u0131n\u0131n sa\u011flayan bir d\u00fczenleyicidir. Seratonin, norefinefrin ve dopamin gibi \u00f6nemli n\u00f6rotransmitterleri par\u00e7alayan bir enzimdir. Bu genin mutasyonu ile Brunner Sendromu g\u00f6r\u00fclmektedir. Otizmde d\u00fc\u015f\u00fck aktivitesinin g\u00f6r\u00fclmesinin yan\u0131nda; alzheimer, \u015fizofreni, panik bozukluk, sald\u0131rganl\u0131k, maj\u00f6r depresif bozukluk ve hiperaktivite gibi hastal\u0131klara da neden olmaktad\u0131r. <\/p>\n\n\n\n
Brunner Sendromuna sahip olanlar ani ve ge\u00e7ici olan krizlerin yan\u0131nda hafif zihin engeline de sahiptirler. <\/p>\n\n\n\n
MAO-A D\u00fc\u015f\u00fck Aktiviteli Varyant\u0131: Sava\u015f\u00e7\u0131 Geni<\/strong> <\/h2>\n\n\n\n 1993 y\u0131l\u0131nda HG Brunner ve ekibi taraf\u0131ndan Hollandal\u0131 bir ailenin \u00fczerinde yap\u0131lan ara\u015ft\u0131rmada; ailedeki erkek \u00e7ocuklar\u0131n k\u0131zd\u0131klar\u0131nda, bir sorunla kar\u015f\u0131la\u015ft\u0131klar\u0131nda ya da \u00fcz\u00fcld\u00fcklerinde daha agresif davran\u0131\u015flarda bulunduklar\u0131 g\u00f6zlemlendi. Yap\u0131lan ara\u015ft\u0131rmalar sonucunda ise MAO-A eksikli\u011fi nedeniyle bu davran\u0131\u015flar\u0131 g\u00f6sterdikleri a\u00e7\u0131kland\u0131. <\/p>\n\n\n\n
Yap\u0131lan bu ara\u015ft\u0131rmalar ise MAO-A geni \u00e7\u0131kar\u0131larak farelerde de desteklendi. Farelerin daha agresif ve sava\u015f ba\u015flatmaya daha m\u00fcsait olduklar\u0131 g\u00f6r\u00fcld\u00fc. <\/p>\n\n\n\n
Sosyal d\u0131\u015flanmaya maruz kalan ya da istismara u\u011fram\u0131\u015f, MAO-A geninde d\u00fc\u015f\u00fck aktiviteye sahip olan insanlarda sald\u0131rganl\u0131\u011fa e\u011filimin oldu\u011fu g\u00f6r\u00fclm\u00fc\u015ft\u00fcr. D\u00fc\u015f\u00fck aktiviteye neden olan varyant\u0131na Sava\u015f\u00e7\u0131 Geni denilmektedir. Bu ki\u015filer intikam alma duygusuna fazlas\u0131yla sahiptirler ve daha \u00e7ok risk al\u0131rlar. <\/p>\n\n\n\n
T\u00fcm bu bilimsel ara\u015ft\u0131r\u0131lmalar sonucunda art\u0131k genotip ve \u00e7ocuklukta ya\u015fan\u0131lan bir alt sorun neden olarak g\u00f6sterilerek davalara sunulmu\u015f ve su\u00e7u i\u015fleyenin sorumlulu\u011funda olmad\u0131\u011f\u0131na karar verilmi\u015ftir. <\/p>\n\n\n\n
Peki Sadece Genlerimiz mi Bizi Su\u00e7lu Yapar?<\/strong> <\/h3>\n\n\n\n Bir\u00e7ok m\u00fcnazarada su\u00e7lulu\u011fun do\u011fu\u015ftan m\u0131 geldi\u011fini yoksa sonradan m\u0131 \u00f6\u011frenildi\u011fi tart\u0131\u015f\u0131lmaktad\u0131r. Az \u00f6nce sayd\u0131\u011f\u0131m gen mutasyonu nedeniyle su\u00e7lulu\u011fa e\u011filim olsa da bunun yan\u0131nda \u00e7evresel fakt\u00f6rler de vard\u0131r. <\/p>\n\n\n\n
\u00c7ocuklukta ya\u015fan\u0131lan istismar ve aile i\u00e7i \u015fiddet gibi olaylar k\u00fc\u00e7\u00fck ya\u015flarda travmaya neden olmaktad\u0131r. K\u00fc\u00e7\u00fck ya\u015flarda kendilerine \u015fiddet uygulanmas\u0131 ile b\u00fcy\u00fcd\u00fcklerinde onlar da \u015fiddet g\u00f6stermekte, hatta kendi \u00e7ocuklar\u0131na ayn\u0131 travmay\u0131 ya\u015fatmaktad\u0131r. K\u0131sacas\u0131 \u00f6\u011frendiklerini uygulamaktad\u0131rlar. <\/p>\n\n\n\n
Ne kadar gen mutasyonu olsa da sa\u011fl\u0131kl\u0131 bir \u00e7evre ile b\u00fcy\u00fcmek daha sa\u011fl\u0131kl\u0131 bir ya\u015fam\u0131 sa\u011flayacakt\u0131r. <\/p>\n\n\n\n
K\u0131sacas\u0131 genlerimiz bizim hamurumuzu olu\u015ftursa da nas\u0131l bir \u00e7evrede nas\u0131l yeti\u015ftirildi\u011fimiz hamurun yo\u011furulu\u015funu de\u011fi\u015ftirir.<\/em><\/strong> <\/em><\/p>\n\n\n\n Bu konuyla ilgili daha da bilgi almak isterseniz Inside the Warrior Gene <\/em>adl\u0131 National Geographic belgesini izlemenizi tavsiye ediyorum. A\u00e7\u0131klamas\u0131nda ‘Kendi kaderimizi mi kontrol ediyoruz yoksa kaderimiz mi bizi kontrol ediyor?’ <\/em> tam da akl\u0131m\u0131zdaki soruyu canland\u0131rmakta.<\/p>\n\n\n\n <\/em>Siz bu konu hakk\u0131nda ne d\u00fc\u015f\u00fcn\u00fcyorsunuz? Genlerimiz mi bizi y\u00f6netmekte?<\/em><\/strong><\/p>\n\n\n\nKaynak\u00e7a<\/strong><\/p>\n\n\n\n
Sally McSwiggan, Bernice Elger, Paul S Appelbaum\/ The <\/sup> Forensic Use of Behavioral Genetics in Criminal Proceedings: Case of the MAOA-L Genotype, 2016 Nov 4\/ Eri\u015fim tarihi:9 Kas\u0131m 2020<\/p>\n\n\n\nOlivier Cases, Isabelle Seif, Joseph Grimsby, Patricia Gaspar, Kevin Chen, Sandrine Pournin, Ulrike M\u00fcller, Michel Aguet, Charles Babinet, Jean Chen Shih, Edward De Maeyer\/ Aggressive Behavior and Altered Amounts of Brain Serotonin and Norepinephrine in Mice Lacking MAOA,2010 Mar 24\/ Eri\u015fim tarihi:11 Kas\u0131m 2020<\/p>\n\n\n\n
Regina Waltes, Andreas G Chiocchetti, Christine M Freitag\/ The Neurobiological Basis of Human Aggression: A Review on Genetic and Epigenetic Mechanisms,2015 Oct 22\/ Eri\u015fim tarihi:4 Kas\u0131m 2020
<\/p>\n\n\n\n
HG Brunner, M Nelen, XO Breakefield, HH Ropers, BA van Oost\/ Abnormal Behavior Associated with a Point Mutation in the Structural Gene for Monoamine Oxidase A, 1993 Oct 22\/ Eri\u015fim tarihi: 9 Kas\u0131m 2020 <\/p>\n\n\n\n
S H Dinwiddie\/Genetics, Antisocial Personality, and Criminal Responsibility,1996\/ Eri\u015fim tarihi:9 Kas\u0131m<\/p>\n\n\n\n
<\/p>\n\n\n\n
<\/p>\n\n\n\n
<\/p>\n\n\n\n
<\/h1>\n\n\n\n
<\/p>\n\n\n\n
<\/p>\n\n\n\n
<\/p>\n","protected":false},"excerpt":{"rendered":"
DNA’m\u0131z kimli\u011fimizi olu\u015fturmaktad\u0131r. Ki\u015fili\u011fimizi, d\u0131\u015f g\u00f6r\u00fcn\u00fc\u015f\u00fcm\u00fcz\u00fc, hastal\u0131klar\u0131m\u0131z\u0131, bizi olu\u015fturmaktad\u0131r. Anne ve babadan ald\u0131\u011f\u0131m\u0131z genlerin birle\u015fmesidir. Yani ailemizin kal\u0131tsal miras\u0131 bizim<\/p>\n","protected":false},"author":386,"featured_media":8429,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[2173],"tags":[95,894,1345,274,149,1228,115,810,142,1075,956],"acf":[],"views":975,"_links":{"self":[{"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/posts\/8411"}],"collection":[{"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/users\/386"}],"replies":[{"embeddable":true,"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/comments?post=8411"}],"version-history":[{"count":22,"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/posts\/8411\/revisions"}],"predecessor-version":[{"id":11334,"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/posts\/8411\/revisions\/11334"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/media\/8429"}],"wp:attachment":[{"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/media?parent=8411"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/categories?post=8411"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/tags?post=8411"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
Peki Sadece Genlerimiz mi Bizi Su\u00e7lu Yapar?<\/strong> <\/h3>\n\n\n\n
Bir\u00e7ok m\u00fcnazarada su\u00e7lulu\u011fun do\u011fu\u015ftan m\u0131 geldi\u011fini yoksa sonradan m\u0131 \u00f6\u011frenildi\u011fi tart\u0131\u015f\u0131lmaktad\u0131r. Az \u00f6nce sayd\u0131\u011f\u0131m gen mutasyonu nedeniyle su\u00e7lulu\u011fa e\u011filim olsa da bunun yan\u0131nda \u00e7evresel fakt\u00f6rler de vard\u0131r. <\/p>\n\n\n\n
\u00c7ocuklukta ya\u015fan\u0131lan istismar ve aile i\u00e7i \u015fiddet gibi olaylar k\u00fc\u00e7\u00fck ya\u015flarda travmaya neden olmaktad\u0131r. K\u00fc\u00e7\u00fck ya\u015flarda kendilerine \u015fiddet uygulanmas\u0131 ile b\u00fcy\u00fcd\u00fcklerinde onlar da \u015fiddet g\u00f6stermekte, hatta kendi \u00e7ocuklar\u0131na ayn\u0131 travmay\u0131 ya\u015fatmaktad\u0131r. K\u0131sacas\u0131 \u00f6\u011frendiklerini uygulamaktad\u0131rlar. <\/p>\n\n\n\n
Ne kadar gen mutasyonu olsa da sa\u011fl\u0131kl\u0131 bir \u00e7evre ile b\u00fcy\u00fcmek daha sa\u011fl\u0131kl\u0131 bir ya\u015fam\u0131 sa\u011flayacakt\u0131r. <\/p>\n\n\n\n
K\u0131sacas\u0131 genlerimiz bizim hamurumuzu olu\u015ftursa da nas\u0131l bir \u00e7evrede nas\u0131l yeti\u015ftirildi\u011fimiz hamurun yo\u011furulu\u015funu de\u011fi\u015ftirir.<\/em><\/strong> <\/em><\/p>\n\n\n\n Bu konuyla ilgili daha da bilgi almak isterseniz Inside the Warrior Gene <\/em>adl\u0131 National Geographic belgesini izlemenizi tavsiye ediyorum. A\u00e7\u0131klamas\u0131nda ‘Kendi kaderimizi mi kontrol ediyoruz yoksa kaderimiz mi bizi kontrol ediyor?’ <\/em> tam da akl\u0131m\u0131zdaki soruyu canland\u0131rmakta.<\/p>\n\n\n\n <\/em>Siz bu konu hakk\u0131nda ne d\u00fc\u015f\u00fcn\u00fcyorsunuz? Genlerimiz mi bizi y\u00f6netmekte?<\/em><\/strong><\/p>\n\n\n\n Kaynak\u00e7a<\/strong><\/p>\n\n\n\n Olivier Cases, Isabelle Seif, Joseph Grimsby, Patricia Gaspar, Kevin Chen, Sandrine Pournin, Ulrike M\u00fcller, Michel Aguet, Charles Babinet, Jean Chen Shih, Edward De Maeyer\/ Aggressive Behavior and Altered Amounts of Brain Serotonin and Norepinephrine in Mice Lacking MAOA,2010 Mar 24\/ Eri\u015fim tarihi:11 Kas\u0131m 2020<\/p>\n\n\n\n Regina Waltes, Andreas G Chiocchetti, Christine M Freitag\/ The Neurobiological Basis of Human Aggression: A Review on Genetic and Epigenetic Mechanisms,2015 Oct 22\/ Eri\u015fim tarihi:4 Kas\u0131m 2020 HG Brunner, M Nelen, XO Breakefield, HH Ropers, BA van Oost\/ Abnormal Behavior Associated with a Point Mutation in the Structural Gene for Monoamine Oxidase A, 1993 Oct 22\/ Eri\u015fim tarihi: 9 Kas\u0131m 2020 <\/p>\n\n\n\n S H Dinwiddie\/Genetics, Antisocial Personality, and Criminal Responsibility,1996\/ Eri\u015fim tarihi:9 Kas\u0131m<\/p>\n\n\n\n <\/p>\n\n\n\n <\/p>\n\n\n\n <\/p>\n\n\n\n <\/p>\n\n\n\n <\/p>\n\n\n\n <\/p>\n","protected":false},"excerpt":{"rendered":" DNA’m\u0131z kimli\u011fimizi olu\u015fturmaktad\u0131r. Ki\u015fili\u011fimizi, d\u0131\u015f g\u00f6r\u00fcn\u00fc\u015f\u00fcm\u00fcz\u00fc, hastal\u0131klar\u0131m\u0131z\u0131, bizi olu\u015fturmaktad\u0131r. Anne ve babadan ald\u0131\u011f\u0131m\u0131z genlerin birle\u015fmesidir. Yani ailemizin kal\u0131tsal miras\u0131 bizim<\/p>\n","protected":false},"author":386,"featured_media":8429,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[2173],"tags":[95,894,1345,274,149,1228,115,810,142,1075,956],"acf":[],"views":975,"_links":{"self":[{"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/posts\/8411"}],"collection":[{"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/users\/386"}],"replies":[{"embeddable":true,"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/comments?post=8411"}],"version-history":[{"count":22,"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/posts\/8411\/revisions"}],"predecessor-version":[{"id":11334,"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/posts\/8411\/revisions\/11334"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/media\/8429"}],"wp:attachment":[{"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/media?parent=8411"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/categories?post=8411"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blog.ulubat.org\/index.php\/wp-json\/wp\/v2\/tags?post=8411"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
Sally McSwiggan, Bernice Elger, Paul S Appelbaum\/ The <\/sup> Forensic Use of Behavioral Genetics in Criminal Proceedings: Case of the MAOA-L Genotype, 2016 Nov 4\/ Eri\u015fim tarihi:9 Kas\u0131m 2020<\/p>\n\n\n\n
<\/p>\n\n\n\n<\/h1>\n\n\n\n